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1、Clinicalstudyonpainlessgastroscopyin1000patients李爽张霞】,张建培I,陈锡美I(1.同济犬学附属同济医院消化内科,上海200065;2.宝山中心医院消化内科,上海201900)LiShuang12,ZhangXia1,ZhangJian-pei1,ChenXi-mei1(l.Dept.ofGastroenterology,TongjiHospital,TongjiUniversity,Shanghai200065,China;2.Dept,ofGastroenterology,BaoshanDistrictCenterHospital,
2、Shanghai201900,China)第一作者:李爽,1976.2,男,主治医师,上海宝山中心医院消化内科(上海宝山区友谊路181号,201900),现于上海同济大学附属同济医院就读同等学历硕士研究牛。电了邮箱:myydngyang2003@sina.com,电话:15800647366,通信地址:上海M宝山区双庆路85弄19号402室,邮编:201900【摘要】目的探讨无痛冉镜检查术的优越性和安全性。方法应川丙泊酚行无痛鬥镜检査1000例,帘规胃镜检査1000例作为对照。记录所有患者不适反应以及心率(11R)、血氧饱和度(SpOJ、血压(Bp)的变化。结果无痛组患者咳嗽、咽痛等
3、不适反应的发生率明显低于常规胃镜检査组,两者冇显著性差界(P<0.01);96%的无痛纽患者愿意再次接受胃镜检查,较常规组(22.0%)冇显著性差异(P<0.01)。两组检查前或麻醉前HR、SBP、DBP、SpO/均正常,无痛组检查中、检查后上述指标同检查前比较无显若性差异(P>0.05),常规组检查中HR、SBP、DBP升高,与检查前差异有显苦意义(P<0.05),检查中两组HR、SBIDBP比较,差异有显著意义(P〈0.05)。结论无痛胃镜检查是一种安全、有效的检查方法。【关键词】鬥镜检查;丙泊酚;麻醉Clinicalstudyonpainlessgastroscopyin10
4、00patients[Abstract]ObjectiveToinvestigatethesuperiorityandsafetyofpainlessgastroscopy.Methods1000paticntsinpainlcssgastroscopygroupweretideatedwithpropofo1.Controlgroupcomprised1000normalgastroscopysubjects・Procedurerelatedparameters,suchascougheindanginawereprospectivelyassessed.Vitalsigns(he
5、artrate,bloodpressureandoxygensaturation)werecontinuouslymonitoredinal1patients.RESULTSTheincideneerateofcoughandanginainpainlessgastroscopygroupweresignificantlowerthanthoseincontrolgroup(P<0.01).96%patientsinpainlessgastroscopygroupcompareswith22%paticntsincontrolgroupcanacceptthesameoperatio
6、nagain(P〈0・01)・Heartrate,bloodpressureandoxygensaturationwerenorma1beforetheprocedureinal1patier)ts・Thevitalsignshadnosignificantchangedurir)gtheprocedure,afteritorbeforeitinpainlessgastroscopygroup・Heartrate,diastolicpressureandoxygensaturationincreasedsignificantduringtheprocedurethcinbeforei
7、tinnormalgtislroscopygroup(P〈0・05)・lletirtrate,diastolicpressureandsystolicpressureweresignificantdifferentduringtheprocedurebetweentwogroups(P<0.05).ConclusionPainlessgastroscopyissafeandeffective・[Keywords】painlessgastroscopy;Pr