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1、高龄患者HCG日LH值与体外受精胚胎移植结局的关系【摘要】目的探讨高龄患者绒毛膜促性腺激素(HCG)H的黄体生成素(L1I)水平与体外受精胚胎移植(IVFET)治疗结局的关系。方法回顾分析2009年1月至2014年12月女方年龄238周岁,在柳州市妇幼保健院生殖中心接受长方案促排卵治疗370个新鲜移植周期,统计软件作图分析LH值与宫内妊娠率关系,根据SPSS统计软件的系统聚类分析分为A、B、C、D共4组。比较4组患者的年龄、不孕年限、窦卵泡数、降调天数、Gn总量、Gn天数、基础激素、HCG日子宫内膜厚度、内膜类型、获卵数、成熟卵数、移植胚胎个数、移植胚胎优胚率、临床妊娠率、
2、流产率、抱婴回家率。结果根据SPSS统计软件作图结果,妊娠率随着HCG日LH值的增加先增高后降低。4组患者年龄、1ICG日子宫内膜厚度、移植胚胎数、移植优胚率、流产率差异无统计学意义(P>0.05),B组与D组比较妊娠率、抱婴回家率差异有统计学意义(P<0.008)o结论高龄患者辅助生殖新鲜移植妊娠率随着HCG日LH值的增加而先增高后降低,HCGHLH值在0.76-1.77之间可获得较好临床妊娠率和抱婴回家率。【关键词】年龄;辅助生殖;黄体生成素;妊娠结局中图分类号:R321.1文献标识码:ADOI:10.3969/j.issn.10031383.2015.05.011Re
3、lationshipbetweenLHvalueinHCGdayandoutcomeofinvitrofertilizationandembryotransferinagedpatients[HJ1][HJ]XULixiang,TANGYongmei,WEILihong,QINZuxing,WEIJihong(LiuzhouMaternalandChildHospital,Liuzhou535000,Guangxi,Chirm)[HJ1][HJ]【Abstract]ObjectiveToinvestigatetherelationshipbetweenluteinizing
4、hormone(LIDlevelinhumanchorionicgonadotropin(1ICG)dayandthetreatmentoutcomeofinvitrofertilizationandembryotransfer(IVFET)ofagedpatients・MethodsRetrospectiveanalysiswasperformedinwomenwhoaged38orabove,receiving370freshtransfercyclesoflongprotocolovulationinductioninReproductiveCenterofMater
5、nalandChildHea1thHospitalofLiuzhoufromJanuary,2009toDecember,2014.StatisticalanalysisandgraphingwasusedtodealwiththerelationshipbetweenLHlevelanduterinepregnancyrate,andallthewomenweredividedintogroupA,groupB,groupCandgroupDaccordingtohierarchicalclusteranalysisinSPSSstatisticalsoftware・Th
6、en,ages,durationofinfertility,antralfolliclecount,daysoffallingtone,Gnamount,Gndays,foundationhormone,endometrialthicknessinHCGday,endometrialpattern,numbersofretrievedoocytes,numbersofmaturationoocytosaswellasnumbersofembryotransfer,highqualifiedembryorateofembryotransfer,clinicalpregnanc
7、yrate,abortionrateandtakehomebabyratewerecomparedbetweengroups・ResultsResultsofSPSSstatisticalanalysisandgraphingshowedthatpregnancyratefirstincreasedandthendecreasedwiththeincreaseofLHvalueinHCGday.Differenceofages,endometrialthicknessinHCGday,numbersofembryo