妊娠合并梅毒孕期治疗临床分析

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1、妊娠合并梅毒孕期治疗临床分析【关键词】妊娠【摘要】目的通过对妊娠合并梅毒孕妇的分组临床分析探讨梅毒筛查试验及孕期治疗的临床意义。方法对34例孕期治疗（治疗组）和19例孕期未经治疗（对照组）的妊娠合并梅毒产妇分组进行孕周、产后出血、新生儿出生体重、新生儿窒息、围产儿死亡、RPR滴定度对比分析。结果产后出血两组间无差异，孕周及新生儿出生体重对照组均显著低于治疗组（P均<0.01）,新生儿窒息率对照组高于治疗组（P〈0.05）,围产儿死亡6例均发生在对照组,RPR滴定度对照组高于治疗组（P<0

2、.05）o镒孕期RPR筛查及孕期驱梅治疗对于降低围产儿死亡、改善围产儿预后具有重要意义。〈Pstyle="TEXT-INDENT:24px">关键词梅毒妊娠筛查孕期治疗〈Pstyle=，，TEXT-INDENT:24px"align=center>Clinicalanalysisofpregnancytreatmentinpregnantwomeninfectedbysyphilisduringpregnancy

3、align=center>ZhengWenjue,LiuBingkunMaternityandChildHealthHospitalofYangpuDistriet,Shanghai,200082.〈Pstyle二〃TEXT-INDENT:24px，z>[Abstract]ObjectiveToinvestigatetheclinicalsignificanceinscreeningofsyphilisandtreatmentinpreg~nancythrough

4、clinicalanalysisgroupbygroupofpregnantwomeninfectedbysyphilisduringpregnancy.MethodsAcomparativeanalysisontherelativedataofpregnancyweek、postpartumhaemorrhagenewbornbirthweightsnewbornasphyxiarate^perinatalmortalityandRPRtitrationdegreewascarriedoutbetweencontrolgroupof19p

5、regnantwomeninfectedbysyphiliswhohadnotbeentreatedandtreatinggroupof34pregna.ntwomeninfectedbysyphilisbuthadbeentreated.ResultsTherewasnodifferencebetweentwogroupsinpostpartumhaemorrhage・Pregnancyweekandnewbornbirthweightincontrolgroupwereremarkablelowerthanthoseintreating

6、group(P<0.01)・Newbornasphyxiarateincontrolgroupwashigherthanthatintreatinggroup(P<0.05)・Allof6perinatalmortalityoccurredincontrolgroup.RPRtitrationdegreeincontrolgroupwashigherthanthatintreatinggroup(P<0.05)・ConclusionRPRscreeningandtreatmentofsyphilisinpregnancyhaveveryim

7、portantsignificanceindecreasingperinatalmortalityandimprovingperinataiprognosis・〈Pstyle二〃TEXTTNDENT:24px〃>Keywordssyphilispregnancyscreeningtreatmentinpregnancy梅毒是由梅毒螺旋体通过直接接触感染的高度传染的性传播疾病。妊娠合并梅毒可通过胎盘引起宫内感染，导致流产、早产、死胎、新生儿死亡或先天梅毒儿出生。对围产儿危害极大，是高危妊娠

8、的重点监护对象之一[1]o我院产科自2000年1月〜2002年6月共收治妊娠合并梅毒产妇53例，现将临床资料分析如下。l资