葡萄糖酸锌结合山莨菪碱治疗小儿轮状病毒性肠炎的临床效果观察

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1、葡萄糖酸锌结合山董君碱治疗小儿轮状病毒性肠炎的临床效果观察【摘要】目的：观察葡萄糖酸锌结合山萇蓉碱治疗小儿轮状病毒性肠炎的临床效果，探究其联合应用价值。方法：选取2012年10月-2013年1月本科收治的70例确诊为小儿轮状病毒肠炎的患儿，按照随机数字表法将其分为对照组和试验组各35例，对照组给予常规治疗，试验组在其基础上给予葡萄糖酸锌结合山董君碱进行治疗，观察比较两组治疗效果、病毒转阴率和平均病程时间。结果：试验组的总有效率94.3%明显高于对照组的74.3%,病毒转阴率68.6%明显高于对照组的42.9%,差异均有统计学意义(P<0.05),且试验

2、组的平均病程(3.48±0.75)d明显短于对照组的(5.24±0.93)d,差异有统计学意义(PvO.OOl)。结论：葡萄糖酸锌结合山罠君碱治疗小儿轮状病毒性肠炎的治疗效果比常规的方案更加有效，并且可以缩短病程，提高治愈率，降低患儿并发症的发生，值得临床推广。【关键词】葡萄糖酸锌；山董蓉碱；小儿轮状病毒性肠炎；病程ClinicalEffectObservationofZincGluconateCombinedwithAnisodamineinTreatmentofChildrenwithRotavirusEnteritis/GUZheng-ping.

3、//MedicalInnovationofChina,2014,11(16)：057-059[Abstract]Objective：Toobservetheclinicaleffectofzincgluconatecombinedwithanisodamineintreatmentofchildrenwithrotavirusenteritis,andexploreitscombinedapplicationvalue.Method：70childrendiagnosedasrotavirusenteritisinourdepartmentfromOc

4、tober2012toJanuary2013wereselected,theywererandomlydividedintothecontrolgroupandtheexperimentalgroupaccordingtotherandomnumbertablemethod,35casesineachgroup.Thecontrolgroupwasgivenconventionaltherapy?theexperimentalgroupwasgivenzincgluconatecombinedwithanisodamineonthebasisofthe

5、controlgroup.Theeffectoftreatment,thevirusclearancerateandaveragedurationbetweenthetwogroupswereobservedandcompared.Result：Thetotalefficiencyofexperimentalgroupwas94.3%,itwassignificantlyhigherthan74.3%ofthecontrolgroup,thevirusclearancerateofexperimentalgroupwas68.6%,itwassigni

6、ficantlyhigherthan42.9%ofthecontrolgroup,thedifferenceswerestatisticallysignificant(P<0.05).Andtheaveragedurationofexperimentalgroupwas(3.48±0.75)d,itwassignificantlyshorterthan(5.24±0.93)dofthecontrolgroup,thedifferencewasstatisticallysignificant(P<0.001)・Conclusion：Thetreatmen

7、teffectofZincgluconatecombinedwithanisodamineintreatmentofchildrenwithrotavirusenteritisismoreeffectivethantheconventionalscheme,andcanshortenthecourseofdisease,improvethecurerate,reducetheincidenceofcomplications,isworthyofclinicalpromotion.【Keywords】Zincgluconate；Anisodamine；C

8、hildrenwithrotavirusenteritis；CourseofdiseaseFi