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1、脑电双频指数评估心肺复苏后患者预后【摘要】目的探讨脑电双频指数(BIS)监测在评估心肺复苏后患者预后的意义。方法选择32例心肺复苏后72h仍然昏迷的患者,行BIS监测,并行格拉斯哥评分(GCS)及急性生理及慢性健康状况评分系统(APACHEII),将BIS值与GCS评分、APACHEII评分进行相关性分析。将患者分为2组:预后良好组(n=7);预后不良组(「25),比较两组的BIS值、GCS评分、APACHEII评分。计算BIS的曲线下面积及对预后判断的截点。结果本组患者30d存活率31.25%„BIS值与GCS评分呈明显正相关(—0.707,P=0.000);预后良好组与预后不良组的BIS
2、值比较,差异具有统计学意义(P=0.000)oBIS曲线下面积为0.943,当BISW60时,其预测心肺复苏后患者发生预后不良的敏感度为100%;特异度为88%。结论:BIS监测可作为心肺复苏后患者预后评估的一个指标。【关键词】脑电双频指数;心肺复苏;预后Assessmenttheprognosisofpatientsaftercardiopulmonaryresuscitationwithbispectralindex.ZHOUPing,DONGYun,WANGJian-dong,CHENYou-dai,ZHANGXiao-hong,LIYi,DENGLei,FENGXuan-lin,SU
3、Ming-hua,LIJun-ying.EmergencyIntensiveCareUnit,SichuanProvincialPeople7sHospital,Chengdu,610072,ChinaCorrespondingauthor:DONGYun,Email:dongyun0511@163.com【Abstract】ObjectiveTostudythevalueofbispectralindex(BIS)inpredictingtheprognosisofpatientsaftercardiopulmonaryresuscitation(CPR)・MethodsThirty-tw
4、ocomapatients72hoursafterCPRwereenrolledforstudywithmonitoringthechangesofBIS,glasgowcomascale(GCS)andacutephysiologyandchronichealthevaluationscoringsystem(APACHEII),andsubsequentlythemonitoreddataweredocumentedandanalyzed・Thepatientsweredividedinto2groups:goodprognosisgroup(n=7)andpoorprognosisgr
5、oup(n=25),andcomparisonsofBIS,GCSandAPACHEIIweremadebetweentwogroups・Theareaunderthecurve(ROC,AUC)ofBISandtheinterceptpointforassessingprognosiswerecalculated.ResultsThe30-daysurvivalrateinthisstudywas31.25%.ThepositivecorrelationbetweenthevaluesofBISandGCSwereobvious(r=0.707,P=0.000)・ComparisonofB
6、ISbetweentwogroupsshoweddifferencewasstatisticallysignificance(P=0.000)・TheareaundertheROCofBISwas0.943.WhenBISW60,thesensitivityofpredictingpoorprognosisofpatientsafterCPRwas100%;thespecificitywas88%・ConclusionsBISmonitoringcouldbeahighsensitiveindicatorofevaluatingprognosisofpatientsaftercardiopu
7、lmonaryresuscitation.[Keywords1Bispectralindex;Cardiopulmonaryresuscitation;Prognosis随着心肺复苏术(CPR)规范化培训的加强,以及心肺复苏术的不断发展,心肺复苏的质量和成功率得到了很大的提高。但临床CPR的总体效果依然不满意,出院存活率自2005年以来并无实质性的提高[1]。复苏成功后的脑损害是影响患者完全康复的重大障碍[2