21.Diagnosis and treatment of small intestinal bacterial overgrowth

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1、ExpertReviewofGastroenterology&HepatologyISSN:1747-4124(Print)1747-4132(Online)Journalhomepage:http://www.tandfonline.com/loi/ierh20DiagnosisandtreatmentofsmallintestinalbacterialovergrowthFrancescaRomanaPonziani,VivianaGerardi&AntonioGasbarriniTocitethisarticle:FrancescaRomanaPonziani,Vivian

2、aGerardi&AntonioGasbarrini(2016)Diagnosisandtreatmentofsmallintestinalbacterialovergrowth,ExpertReviewofGastroenterology&Hepatology,10:2,215-227,DOI:10.1586/17474124.2016.1110017Tolinktothisarticle:http://dx.doi.org/10.1586/17474124.2016.1110017Publishedonline:04Dec2015.Submityourarticletothi

3、sjournalArticleviews:485ViewrelatedarticlesViewCrossmarkdataCitingarticles:1ViewcitingarticlesFullTerms&Conditionsofaccessandusecanbefoundathttp://www.tandfonline.com/action/journalInformation?journalCode=ierh20Downloadby:[WenzhouMedicalCollege]Date:06April2017,At:00:26EXPERTREVIEWOFGASTROENT

4、EROLOGY&HEPATOLOGY,2016VOL.10,NO.2,215–227http://dx.doi.org/10.1586/17474124.2016.1110017REVIEWDiagnosisandtreatmentofsmallintestinalbacterialovergrowthFrancescaRomanaPonziani,VivianaGerardiandAntonioGasbarriniInternalMedicineandGastroenterology,AgostinoGemelliHospital,Rome,ItalyABSTRACTARTIC

5、LEHISTORYAhugenumberofbacteriaarehostedinthegastrointestinaltract,followingagradientincreas-Received23August2015ingtowardsthecolon.GastricacidsecretionandintestinalclearanceprovidethequalitativeandAccepted15October2015quantitativepartitioningofintestinalbacteria;smallintestinalbacteriaovergro

6、wth(SIBO)occursKEYWORDSwhenthesebarriermechanismsfail.DiagnosisofSIBOischallengingduetothelowspecificityofSmallintestinalbacteriasymptoms,thefrequentassociationwithotherdiseasesofthegastrointestinaltractandtheovergrowth(SIBO);glucoseabsenceofoptimalobjectivediagnostictests.Thetherapeuticappro

7、achtoSIBOisorientedbreathtest;lactulosebreathtowardsresolvingpredisposingconditions,andissupportedbyantibiotictreatmenttorestoretest;rifaximin;antibiotics;thenormalsmallintestinalmicrofloraandbymodificationsofdietaryhabitsforsymptomaticmetage