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1、SPINEVolume30,Number23,pp26212630©2005,LippincottWilliams&Wilkins,Inc.DiscogenicOriginsofSpinalInstabilityFengdongZhao,BS(ClinMed),MS(Orth),*PhillipPollintine,BSc,MSc,PhD,†BarnyD.Hole,BSc,†PatriciaDolan,BSc,PhD,†andMichaelA.Adams,BSc,PhD†StudyDesign.Cadavericmotionsegme
2、ntexperiment.segmentalinstability.Backpainassociatedwithinstabil-Objective.Toshowhowtwophysicalaspectsofdiscitymaybeattributabletostressconcentrationsindegen-degeneration(dehydrationandendplatedisruption)con-erateddiscs.tributetospinalinstability.Keywords:instability,in
3、tervertebraldisc,degenera-SummaryofBackgroundData.Theoriginsofspinaltion,endplatefracture,creep,invitro.Spine2005;30:instabilityanditsassociationswithbackpainareuncertain.2621–2630Methods.Twenty-onecadavericthoracolumbarmo-tionsegmentsaged48to90yearsweresecuredincupsSpi
4、nalinstabilityhasprovokedcontroversyformoreofdentalplasterandloadedsimultaneouslyinbending14andcompressiontosimulatefullflexion,extension,andthan50years.Itisanemotivetermthatmightalarmlateralbendingmovements.Vertebralmovements,re-somepatients,butitisalsoaconvenientlabelf
5、orspinecordedusingatwo-dimensional“MacReflex”motionchangesthatbearsomeassociationtoengineeringin-analysissystem,wereanalyzedtocalculateneutralzonestability.Theconceptisoflittlevalueifappliedindis-(NZ),rangeofmotion(ROM),bendingstiffness(BS),hor-criminatelytopatientswithm
6、echanicalbackpain,butifizontaltranslationalmovements,andthelocationofthecenterofrotation(COR).Intradiscal“stresses”weremea-specificdisorderssuchastrauma,tumors,previoussur-suredbypullingaminiaturepressuretransducerthrough5gery,spondylolysis,andscoliosisarefirstexcluded,th
7、ediscalongitsmidsagittaldiameter.Allexperimentsthentheremainingdegenerativeinstability6maybeawererepeatedaftereachoftwotreatments,whichsimu-7clinicallyusefulconcept.Suchinstabilityusuallyreferslatedphysicalaspectsofdiscdegeneration:creeploadingtobackpainexacerbatedbymov
8、ementandassociatedtodehydratethediscandcompressiveoverloadtodis-rupttheendplate.ResultswereanalyzedusingANOVAw
