Metabolic changes of prefrontal cerebral lobe, white matter and cerebellum in patients with post-stroke depression：A proton

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1、维普资讯http://www.cqvip.comNEURALREGENERATIONRESEARCHVolume3，Issue2，February2008ⅥnsjzsyJ．comMetabolicchangesofprefrontalcerebrallobe，whitematterandcerebelluminpatientswithpost-strokedepression★☆AprotonmagneticresonancespectroscopystudyQinggangXu’，_，HongCao。，Qing

2、weiSong’JianlinWu’，1DepartmentofRadio~gy,F．fstAfiliatedHospitalofDalianMedicalUn~ersity,Dalian116011．L~onmgProvince,cha2DepartmentofRadio~gy,BeringTongRenHospital,CapitalMedicalUn~ersity,Beijing100730,Chma3DepartmentofNeurology,F括fAfiliatedHospitalofDalianMed

3、icalUniversity,DalianT1601T．L~onmgProvince,ChmaAbstractBACKGRoUND：Protonmagneticresonancespectroscopy(H—MRS)non—invasivelydetectschangesinQinggangXu☆。studyingforchemicalsubstancesinthebrain．whichreflectsthepathologicalmetabolism．doctorate。ResidentOBJECTIVE：To

4、investigatechangesinN—acetyl—aspartate(NAA)，choline(Cho)，creatine(Cr)，andphysician。DepartmentofmyoinositolfMIinthegrayandwhitematterofcerebralprefrontallobeandcerebelumofpatientswithRadiology．BeijingTongRenHospita1．CapitalMedicaldi脓rentialdegreesofpost—stroke

5、depression(PSD)usingH—MRS．University，BeijingDESlGN：Acasecontrolstudy．100730ChinaSETTlNG：TheFirstAmriatedHospitaloftheDarianMedicalUniversity．PARTICIPANTS：Atotalof38patientswithstroke(28maleandlOfemalepatients．aged40to79years)OG．CaoH．SongOW。Wuwereselectedfromt

6、heDepartmentofNeurology，lstAmliatedHospital，DalianMedicalUniversity，fromJLMetabolicchanQesofFebruarytoOctoberin2004．AllsubiectsmettheDSM—IVcfitefiaforcerebrovasculardiseaseandprefrontalOereb旧IIobe．whitedepression．ThedegreeofdepressionwasdefinedaccordingtoHami

7、ltoncriteria．38patientswithPSDwerematterandcerebelumInpatientswithpost—strokedividedintotwogroupsaccordingtothetimeafterischemia．20patientsintheacutegroupwithlessthan10depress~n：Aprotonmagneticdaysafterischemicattack(mild：16patients．moderate／severe：4patients)

8、andl8patientsinthechronicresonancespectroscopystudy．groupwithmorethan11daysafterischemicattack(mild：15patients．moderate／severe：3patients)．NeuralRegenRes2008；3(2】：Seventeenhealthyvolunteer