《旋毛虫、丝虫》PPT课件

《《旋毛虫、丝虫》PPT课件》由会员上传分享，免费在线阅读，更多相关内容在教育资源-天天文库。

1、ReviewofintestinalhelminthsAscarislumbricoides(roundworm)似蚓蛔线虫（蛔虫）Trichuristrichiura(whipworm)毛首鞭形线虫（鞭虫）Enterobiusvermicularis(pinworm)蠕形住肠线虫（蛲虫）AncylostomaduodenaleNecatoramericanus(hookworms)钩虫Trichinellaspiralis旋毛形线虫Tissue-blooddwellingnematodes--Filaria

2、丝虫Wuchereriabancrofti班氏吴策线虫Onchocercavolvulus旋盘尾丝虫ThehistoryofTrichinellaspiralisInyear1835，YoungJimPaget,afirstyearmedicalstudentatLondonHospitalMedicalSchool,rushedintotheautopsyroom.The51yr-oldItalianbricklayerwhohaddiedoftuberculosis,andthattheywerenowd

3、issecting,alsohad"sandydiaphragm,"aconditionthatdulledeventhesharpestofscalpels.Well,anyway,whentheyhadallclearedtheroom,Jimquietlystolebackinandremovedasmallbitofmuscletissuefromthediaphragm.Hewasmorethancuriousastothenatureof"sandydiaphragm".Hefirstexamin

4、editwithhistrustyhandlenshecarriedforjustsuchasituation.Hethoughthesawsmallwormscoiledupinsideeachnodule.Uponevenhighermagnification,thepresenceofcoiledwormswasrevealed.(Fromwww.trichinella.org)TrichinellaspiralisJimPagetWormsinthe“sandydiaphragm”Trichinell

5、aspiralisTrichinawormswereobservedinporkin1846byJosephLeidy.Hesavedhundredsoflivesbyrecommendingcookingporkatahighenoughtemperaturetokilltheorganism.Lifecycleworkoutin1850’sByRudolphVirchow.TrichinellacontrolRudolfVirchow(Germany)suggestedmandatorydiagnosis

6、ofallmeatattheslaughterhousesin1877ThishasgreatlyreducedtrichinellosisashumanhealthProblem.WorldwideDistributionParasiticzoonosisFoodborneparasitosisTrichinellaspiralis-cause旋毛虫病trichinosis,trichiniasis,ortrichinelliasisDistributionofTrichinellaspiralisTri

7、chinosisismostcommonintemperateandarcticclimates-highprevalenceinpork-eatingareasoftheworld.arctictemperateAdultsofTrichinellaspiralisAdults:small,1.5~4mmLarva:femalesgivebirthtolarva(Eggs:hatchinuterus子宫)stichosomeHatchedLarva杆状体成虫形态在诊断上无意义！特点：直接产幼虫Encyste

8、dlarva幼虫囊包--infectivestage0.25~0.5mm×0.21~0.42mmLemonshape1~2larvainthecystLifecycleAdultfemaleinmucosaofsmallintestineTrichinacystsinskeletalmuscle骨骼肌Pathogenisis3stages：1.Invasion–1weekfirstsymptomsa