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1、#598#临床放射学杂志2006年第25卷第7期ü中枢神经放射学þ室管膜下巨细胞星形细胞瘤的MRI诊断*韩建成,高培毅,林燕,徐磊,田同德,杨智君=摘要>目的研究室管膜下巨细胞星形细胞瘤(SGCA)的MRI表现,探讨MRI对该病的诊断价值。资料与方法回顾性分析经手术病理证实的9例SGCA的临床资料和MRI表现,其中男4例,女5例,年龄4~23岁,平均12.9岁。全部病例术前均行MRI平扫和增强检查。结果所有肿瘤均位于侧脑室孟氏孔附近,3例呈类圆形,6例呈轻度分叶状。平扫T1WI为等或稍低信号,T2WI为等或稍高信号,9例均可见肿瘤周
2、边点状或结节状钙化信号,2例肿瘤内部可见长T1、长T2小囊状信号;增强扫描,肿瘤呈明显均匀或不均匀强化。7例可见室管膜下结节,3例可见皮质结节。结论SGCA的MRI表现有一定特征性,有助于术前诊断。=关键词>室管膜下巨细胞星形细胞瘤脑肿瘤磁共振成像MRIDiagnosisofSubepengdymalGiantCellAstrocytomaHANJiancheng,GAOPeiyi,LINYan,etal.NeuroimagingCenter,BeijingNeurosurgicalInstitute,TheCapitalUnive
3、rsityofMedicalScience,Beijing100050,P.R.China=Abstract>ObjectiveTostudyMRIfindingsofsubependymalgiantcellastrocytomaandevaluateitsdiagnosticvalueinsubependymalgiantcellastrocytoma.MaterialsandMethodsClinicaldataandMRIfindingsin9patientsofsubependymalg-iantcellastrocyto
4、ma(4maleand5female;ranginginagefrom4to23yearsold;meanage:12.9years)withpathologicallyprovedwereretrospectivelyanalyzed.PreandpostMRscanswereperformedinallpatients.ResultsAlltumorswerelocatedneartheforamenofmonro,3patientswereroundlikeand6patientswereslightlylobulatedin
5、shape.ThetumorswereappearedisoorhypointensityonT1WIandisoorhyperintensityonT2WI,therewerepunctateornodularcalcificationsintheborderofthetumorsinallcases,andsmallcysticchangesinthecenterofthetumorsin2patients.Afterinjectionofcontrastagent,thetumorsweremarkedlyhomogeneou
6、sorheterogeneousenhancement.Subependymalnoduleswereseenin7patients,andcorticaltuberswereobservedin3patients.ConclusionTheMRIfindingsofsubependymalgiantcellastrocytomaarecharacteristic,whichplayanveryimportantroleinmakingacorrectpreoperativediagnosis.=Keywords>Subependy
7、malgiantcellastrocytomaBraintumorMagneticresonanceimaging室管膜下巨细胞星形细胞瘤(subependymalgiantCA的MRI表现予以分析,旨在提高对该病的认识。cellastrocytoma,SGCA)是一种伴发于结节性硬化(tuberoussclerosis,TS)的少见的中枢神经系统良性1资料与方法[1,2]肿瘤,其发生率占所有TS患者的5%~14.3%。搜集本院2001至2005经手术病理证实的SGCA在WHO2000年中枢神经系统肿瘤组织学类型中,患者9例,男4例
8、,女5例,年龄4~23岁,平均12.9其被归属于神经上皮肿瘤中的星形细胞肿瘤。临床岁。临床表现为头痛、恶心、呕吐5例,发作性意识[1~3]表现多为颅内压增高的症状和体征。MRI对本丧失2例,间断抽搐2例,视力下降3例。体检发现病具有重