抗血小板治疗对FIREBIRD支架置入术后的中期疗效的观察

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1、抗血小板治疗对FIREBIRD支架置入术后的中期疗效的观察抗血小板治疗对FIREBIRD支架置入术后的中期疗效的观察摘要目的：探讨抗血小板治疗对Firebird支架置入术后冠心病患者中期临床疗效。方法：纳入2004至2007年在我院置入Firebird国产雷帕霉素洗脱支架的病人635例，分为三大组：阿斯匹林lOOmg+波立维3月以内、3月一6月、6月一1年组，记录各组患者基础、临床、介入治疗情况及临床随访结果，实际随访例数为607例(共植入支架1004枚)，平均随访时间为28个月，临床随访率为95．6％。结果：(1)三组患者主要心血管不良事件(MACE)发生率

2、分别为12．O％、10．8％、5．6％，三组间有统计学意义差别(PO．05)。结论：(1)国产Firebird雷帕霉素洗脱支架植入术后延长口服氯吡格雷时间至12个月甚至更长将更有利于降低心血管事件的发生。(2)国产Firebird雷帕霉素洗脱支架植入术后延长口服氯吡格雷时间至12个月甚至更长不增加药物不良事件的发生率。关键词：药物洗脱支架；氯吡格雷；主要心血管不良事件抗IfⅡ,b板治疗对FI

3、REBIRD支架置入术后的中期疗效的观察2006级硕』j研究生学位论文TheMedium—-termEfficacyofAntiplateletTherapyinPatientsWithCoronaryHeartDiseaseTreatedbyFirebirdStentsAbstractobjective：Toevaluatethemedium—termefficacyofAntiplatelettherapyinpatientswithcoronaryheartdiseasetreatedbyFirebirdstentsMethods：From2004to2

4、007，atotalof635consecutivepatientswithCADwhoreceivedFirebirdstentimplantationinourhospital．ThesepatientsweredividedintothreegroupsbasedonthetimeofapplyingasprinandClopidogrel．Majoradversecardiacevents(MACE)includingcardiacdeath，non-fatalmyocardialinfarction，heartfailortargetvesselre

5、vascularizationinClinicalfollow-upafterinitialprocedurewerecomparedamongthesethreegroups．Result：(1)Meanfollow-updurationwas28monthsafterstentimplanting．RateofMACEoccurrenceinthegroupofapllyingasprinandClopidogrelover6months(5．6％)weremuchlowerthanothergroups，therewassignificantdiffer

6、enceamongthesegroups(12．O％、10．8％，氏O．05)．(2)Rateofnon—fatalmyocardialinfarction，heartfail，targetvesselrevascularizationandbleedingoccurrenceinthegroupofapllyingasprinandClopidogrelover6monthsweremuchlowerthanothergroups，therewassignificantdifferenceamongthesegroups(氏O．05)．(3)Butthera

7、teofcardiacdeathandanginawasnotsignificantdifferenceamongthesegroups(P>O．05)．Conclusion：TheClinicalfollow-upshowthatthegroupofapllyingaspfinandClopidogrelContinueduntil12monthshasadefiniteclinicalefficacyinthe3抗血小板治疗对FIREBIRD支架置入术后的中期疗效的观察patientswithCADwhoreceivedFirebirdstentimpla

8、ntation，whichcanred