几种化合物对蚊香增效活性的筛选

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1、·338·中华卫生杀虫药械2015年8月第21卷第4期ChinJHygInsect＆EquipAug2015Vol.21No.4【论著】·药械研究·几种化合物对蚊香增效活性的筛选1122李慧，刘辉，田向荣，冯俊涛(1．深圳馥稷生物科技有限公司，广东深圳518133;2．西北农林科技大学无公害农药研究服务中心，陕西杨陵712100)摘要:目的寻找和开发高效的蚊香增效剂。方法以淡色库蚊为试虫，采用GB/T13917．4－2009密闭圆筒法、Peet-grady方箱法、GB/T13917．10－2009模拟现场法测定了

2、7种化合物对0．03%四氟甲醚菊酯蚊香和0.05%氯氟醚菊酯蚊香的增效活性。结果采用密闭圆筒法初筛，发现5种化合物对四氟甲醚菊酯蚊香具有增效活性，其中马来酸二丁酯增效活性最高，增效比为1.67;4种化合物对0.05%氯氟醚菊酯蚊香具有增效活性，其中水杨酸乙酯的增效活性最好，增效比为1.53。采用Peet-grady方箱法复筛，发现水杨酸乙酯和马来酸二丁酯对0.03%四氟甲醚菊酯蚊香有增效活性，其增效比分别为1.11、1.10;马来酸二丁酯对0.05%氯氟醚菊酯蚊香的增效活性较水杨酸丁酯好，它们的增效比分别为1.1

3、8、1.06。最后采用模拟现场法测试，发现水杨酸乙酯对0.03%四氟甲醚菊酯蚊香的增效活性较好，其增效比为1.08;马来酸二丁酯对0.05%氯氟醚菊酯蚊香具有较好的增效活性，其增效比为1.07。结论水杨酸乙酯、马来酸二丁酯的增效活性值得进一步研究。关键词:蚊香;增效活性;筛选中图分类号:Ｒ184．31;S482．3文献标识码:A文章编号:1671-2781(2015)04-0338-04Screeningforthesynergismofseveralcompoundstomosquitocoil1122LIHu

4、i，LIUHui，TIANXiang-rong，FENGJun-tao(1.FujiBiotechnologyCo.Ltd．，Shenzhen518133，China;2．BiorationalPesticideＲesearchandDevelopmentCenterofNorthwestAgricultureandForestryUniversity，Yangling712100，China)Abstract:ObjectiveToofferthebasicinformationofsearchingandde

5、velopingefficientmosquito-repellentincensesynergists．MethodsThesynergismofsevencompoundsto0．03%dimefluthrinmosquitocoiland0．05%chlo-rinefluorideethermosquitocoilweretested，accordingtoGB/T13917．4－2009hermeticroundcanistermethod，peet-gradychambermethodandGB/T13

6、917．10－2009mimicfieldtoCulexpipienspallensas．ＲesultsThehermeticroundcanistertestshowedthat5compoundsweresynergisticto0．03%dimefluthrinmosquitocoil，dibutylmaleatewasthebestonewiththesynergisticratios1．67．4compoundsweresynergisticto0.05%chlorinefluorideethermos

7、-quitocoil，ethylsalicylatewasthebestonewiththesynergisticratios1.53．Peet-gradychambertestdisplayedthateth-ylsalicylateanddibutylmaleateweresynergisticto0．03%dimefluthrinmosquitocoilwiththesynergisticratios1.11and1.10，respectively;Dibutylmaleatewashighersynerg

8、isticto0.05%chlorinefluorideethermosquitocoilthanbu-tylsalicylate，theirsynergisticratioswere1.18and1.06．Themimicfieldtestindicatedthatethylsalicylatewasbettersynergisticto0.03%dimefluthri