欢迎来到天天文库
浏览记录
ID:36757304
大小:700.66 KB
页数:3页
时间:2019-05-14
《尤瑞克林治疗急性分水岭脑梗死患者的疗效观察Δ》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、Δ尤瑞克林治疗急性分水岭脑梗死患者的疗效观察1*223#a334#b王彬,刘洋,李小圆,王靖,张凤云,马福莲,刘淑芹(1.牡丹江医学院第二附属医院医保科,黑龙江牡丹江157015;2.牡丹江医学院第二附属医院药剂科,黑龙江牡丹江157015;3.牡丹江医学院第二附属医院神经内科,黑龙江牡丹江157015;4.牡丹江医学院第二附属医院老年病科,黑龙江牡丹江157015)中图分类号R743.3文献标志码A文章编号1001-0408(2016)05-0650-03DOI10.6039/j.issn.1001-0408.2016.05.23摘
2、要目的:观察尤瑞克林治疗急性分水岭脑梗死(WSI)的临床疗效。方法:将128例急性(WSI)患者,按随机数字表法分为对照组和治疗组,各64例。对照组患者给予舒血宁注射液15ml加入0.9%氯化钠注射液250ml,ivgtt,qd;治疗组患者采用注射用尤瑞克林0.15PNA单位加入0.9%氯化钠注射液100ml,ivgtt,qd,两组患者均连续治疗14d。观察两组患者治疗前及治疗后3、7、14d神经功能缺损评分和临床疗效,并取两组患者治疗后7、14d血液标本,测定血清补体末端复合体(TCC)水平。结果:治疗后,治疗组患者神经功能缺损评分
3、及总有效率均显著高于对照组,差异有统计学意义(P<0.01);治疗前,两组患者TCC水平比较,差异无统计学意义(P>0.05),治疗后7d,两组患者TCC水平均显著升高,至14d时,又有所下降,且治疗组低于对照组,差异有统计学意义(P<0.05)。结论:尤瑞克林能明显提高急性WSI患者临床疗效,改善患者神经功能缺损症状及TCC水平。关键词尤瑞克林;分水岭脑梗死;神经功能缺损评分;血清补体EfficacyObservationofUrinaryKallidinogenaseintheTreatmentofAcuteCerebralWat
4、ershedInfarct1223334WANGBin,LIUYang,LIXiaoyuan,WANGJing,ZHANGFengyun,MAFulian,LIUShuqin(1.Dept.ofMedicalInsurance,theSecondAffiliatedHospitalofMudanjiangMedicalCollege,HeilongjiangMudanjiang157015,China;2.Dept.ofPharmacy,theSecondAffiliatedHospitalofMudanjiangMedicalCol
5、lege,Heilongji-angMudanjiang157015,China;3.Dept.ofNeurology,theSecondAffiliatedHospitalofMudanjiangMedicalCollege,HeilongjiangMudanjiang157015,China;4.Dept.ofGeriatrics,theSecondAffiliatedHospitalofMu-danjiangMedicalCollege,HeilongjiangMudanjiang157015,China)ABSTRACTOBJ
6、ECTIVE:Toobserveclinicalefficacyofurinarykallidinogenaseinthetreatmentofacutecerebralwatershedin-farct(WSI).METHODS:128patientswithWSIwererandomlydividedintocontrolgroupandtreatmentgroup,eachofthe64cases.ControlgroupwasgivenShuxuening15mladdedinto0.9%Sodiumchloride250ml
7、,ivgtt,qd;treatmentgroupreceivedurinarykallidinogenase0.15PNAaddedinto0.9%Sodiumchloride100ml,ivgtt,qd.Bothgroupsweretreatedforconsecutive14days.Neurologicimpairmentscore(NIHSS)andclinicalefficacywereobservedin2groupsbeforetreatmentand3,7and14daysaftertreatment.Theblood
8、specimenswerecollectedafter7and14daystreatment,todetermineserumlevelsofTCC.RESULTS:Aftertreatment,NIHSSandtota
此文档下载收益归作者所有