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1、HeadacheZengJinshengDepartmentofNeurologyandStrokeCenter,FirstUniversityHospitalofSunYat-SenUniversity1.NationalKeySubject(oneofthetop4Departments)inChinasince2001.2.OneofthefourNationalTrainingandAdvancedCentersforStrokePreventionandTreatmentsince2004Name
2、:JinshengZeng(曾进胜)EducationLevel:Ph.D,MD,EMBA(on-going)Title:Fullprofessor&Director,NeurologyDepartmentandStrokeCenter,thefirstUniversityHospital,SunYet-SenUniversityCellphone:13322800657E-mail:zengjs@pub.guangzhou.gd.cnHEADACHEGENERALCONSIDERATIONS1.Thete
3、rmheadacheencompasstheachesandpainslocatedinthehead,butinpracticeitsapplicationisrestrictedtodiscomfortintheregionofcranialvault.Facialpainsareputasideassomethingdifferent.2.Headacheisasyndromeinducedbydifferentcauses.Whenthepainreceptorsinsensitivestructu
4、rearestimulated,itoccurs.ThecausesofheadacheintracranialdiseasesextracranialdiseasessystemicdiseasespsychogenicdiseasesMIGRAINEMIGRAINEisadisordercharacterizedbyperiodic,commonlyunilateralorbilateral,throbbingheadaches.ETIOLOGY ANDMECHANISMSThespecificcaus
5、eisunknown.Keyfactorsinclude:(1)Hereditaryfactors---familialhistory60%(2)EEGdepression(3)DecreaseofCBF(5-HT1breceptor)(4)IncreaseofplateletaggregationKEYFACTORS(5)Dieteticfactors:chocolate,fattyfoods,oranges,tomatoes,onionsandalcohol,etc.(6)Endocriticfacto
6、rs:Theincidenceofmigraineinfemalesisabouttwicethanthatinmales,andtheheadachestendtooccurduringperiodofpremenstrualtension.(7)Inducement:overwork,hunger,climate,sleeplessnessCLINICALPICTURE1.Migrainewithaura(classic,typical)usheredinbyadisturbanceofneurolog
7、icfunction(photopsia,centralblindness,etc.)followedinafewminutesbyhemicranialor,occasionally,bilateralheadache,nausea,vomiting,allofwhichlastforhoursoraslongasadayortwo.CLINICALPICTURE2.Migrainewithoutaura(common,atypical)unheraldedonsetofhemicranialorgene
8、ralizedheadachewithorwhithoutnauseaandvomiting.CLINICALPICTURE3.Uncommonvariantofmigraine(1)ophthalmoplegicmigraine(2)hemiplegicmigraine(3)basal-arterymigraine(4)MigraineequivalentDIAGN0OSIS1.Diagnosis(1)Head
