肾动态显像评价2型糖尿病肾功能的应用价值

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1、肾动态显像评价2型糖尿病肾功能的应用价值肾动态显像评价2型糖尿病肾功能的应用价值摘要：目的探讨肾动态显像对糖尿病肾功能评估的应用价值,关键词：肾动态显像；2型糖尿病；肾功能；糖尿病肾病theapplicationvalueofrenaldynamicimaginginjudgmentofrenalfunctioninpatientswithtype2diabetesmellitusKONGNing-ning,ZUOShu-yao,WANGDeng-chun,WANGZhi-qiang(DepartmentofNuclear

2、Medicine,TheAffiliatedHospitalofQingdaoUniversityMedicalCollege,Qingdao266003,Shandong,China)Abstract：ObjectiveToevaluaterenaldynamicimaginginjudgmentofrenalfunctionsinpatientswithtype2diabetesmellitussoastoproviderelevantbasisforclinicaldiagnosisandtreatment・Meth

3、odsSixty-sixpatientswithtype2diabetesmellitusclassifiedbytheurinaryalbuminexcretionrate(UAER)into3grope:grope1,grope2,grope3.Thirtynormalpeoplewithoutdiabetesmellituswereineludedintocontrolgrope・Renaldynamicimagingwereperformedonallthesecasesaswe11astheserumcreati

4、nine(SCr)andbloodereanitrogen(BUN)hadbeendone,thesurveyoftheglomerularfiltrationrate(GFR),therenalfunctioncurvepeaktime(tb),thehalfactivitytime(Tl/2),the20minresidualrate(C20),theSCrandBUNhadbeendone；eachgropeoftype2diabetesmellituscomparedwithcontrolgrope,justthe

5、gropeofDM3whoseBUNandSCrwerehigherthanthecontrolgrope；everygropeoftype2diabetesmellitusthetb、Tl/2wereIongerthanthecontrolgrope,andtheC20washigherthancontrolgrope・ResultsTheGFRofeachgropeoftype2diabetesmellituswere95.06±20.78,82.64±18.65,33.77±20.50(ml/min),wereall

6、statisticallylowerthanthecontrolgropewhichGFRwas111.95±15.24(ml/min),(P<0.05,P<0.01andP<0.01)・ConclusionRenaldynamicimagingishelpfulfortheearlydetectionofthechangeofrenalfunctionsinpatientswithtype2diabetesmellitus,judgetheinjuryoftherenalfunctionandproviderelevan

7、tbasisforclinicalpreventionanddiagnosistheDiabeticNephropathy(DN)・Keywords：renaldynamicimaging；type2diabetesmellitus；renalfunction；DiabeticNephropathy糖尿病(DM)的发病率LI渐增高，糖尿病已成为危害人类健康的主要疾病之一。糖尿病肾病是糖乐病的主要并发症之一，也是糖尿病患者的主要死亡原因之一。糖尿病肾病起病隐匿，临床发现往往已发展为后期，且进展迅速，最终发展为肾功能衰竭期。早

8、期发现糖尿病肾病对糖尿病患者的治疗及预后有重要意义。1资料与方法1.1一般资料1.2方法1.2.1仪器及药物2结果2.12型糖尿病对肾功能影响的初步分析2.2止常对照组与糖尿病各组GFR及血Cr、BUN定量分析见表2。2.3对照组与糖尿病各组肾功能曲线参数定量分析结果见表3O3讨论糖尿病肾病是糖尿病放常