非瓣膜性房颤患者卒中评分对比及抗凝治疗分析

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1、授予单位代码10089学号或申请号20123029HebeiMedicalUniversity专业学位非瓣膜性房颤患者卒中评分对比及抗凝治疗分析研究生：吴岩熹导师：刘凡教授专业：内科学二级学院：第二医院2015年3月河北医科大学学位论文使用授权及知识产权归属承诺本学位论文在导师（或指导小组）的指导下，由本人独立完成。本学位论文研究所获得的研究成果，其知识产权归河北医科大学所有。河北医科大学有权对本学位论文进行交流、公开和使用。凡发表与学位论文主要内容相关的论文，第一署名为单位河北医科大学，试验材料、原始数据、申报的专利等知识产权均归河北医科大学所有。否则，承担相应法律责任。研究生签名

2、;年、月2(日河北医科大学研究生学位论文独创性声明本论文是在导师指导下进行的研究工作及取得的研究成果，除了文中特别加以标注和致谢等内容外，文中不包含其他人已经发表或撰M的研究成果，指导教师对此进行了审定。本论文由本人独立撰写，义责自负。目录中文摘要·············································································1英文摘要·············································································4英文缩写·······

3、······································································8研究论文非瓣膜性房颤患者卒中评分对比及抗凝治疗分析前言·············································································9材料与方法····································································9结果···········································

4、··································11附图·············································································13附表·············································································15讨论·············································································17结论··············

5、·······························································21参考文献·······································································21综述房颤患者脑卒中的预防方法及评估体系·······························24致谢···················································································39个人简历··········

6、···································································40中文摘要非瓣膜性房颤患者卒中评分对比及抗凝治疗分析摘要目的：本研究通过CHADS2评分系统以及CHA2DS2-VASc评分系统对2014年4月至2014年12月于河北医科大学第二医院住院的175例非瓣膜性房颤患者进行卒中风险评估，比较两种评估系统评估结果的差异。同时，对非瓣膜性房颤患者抗凝治疗现状加以分析。方法：对象：选择2014年4月至2014年12月于河北医科大学第二医院心内科非瓣膜性房颤住院患者，共175例。其中，药物治疗组138例，平均年龄

7、67.84±13.71岁(34~93岁)，男性79例(57.2%)，女性59例(42.8%)；导管消融术组患者37例，平均年龄62.16±7.66岁(33~73岁)，其中,男性23例(62.2%)，女性14例(37.8%)。方法：收集上述患者，分成药物治疗组(DTG)、导管消融术组(RFCA)，将患者性别、年龄、电话、病案号、入院时间、是否合并高血压、糖尿病、心力衰竭、既往脑卒中及TIA史、血管疾病等危险因素，入院时肝肾功能、既往有无出血史、INR控制情况