血清ctrp3水平与冠状动脉病变严重程度及侧支循环形成的关系

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1、授予单位代码10089学号或中请号20123044HebeiMedicalUniversity硕士学位论文专业学位血清CTRP3水平与冠状动脉病变严重程度及侧支循环形成的关系研究生：胡峥导师：张辉教授专业：内科学二级学院：第二医院2015年3月学位论文使用授权及知识产权归属承诺本学位论文在导师（或指导小组）的指导下，由本人独立完成。本学位论文研究所获得研究成果，其知识产权归河北医科大学所有。河北医科大学有权对本学位论文进行交流、公幵和使用。凡发表与学位论文主要内容有关的论文，第一署名单位为河北医科大学，试验材料、原始数据、申报

2、的专利等知识产权均归河北医科大学所有。否则承担相应的法律责任。研究生签名导师签章：丨,二级学院领导签章：j年月河北医科大学研究生学位论文独创性声明本论文是在导师指导下进行的研究工作及取得的研究成果，除了文中特别加以标注和致谢等内容外，文中不包含其他人已经发表或撰写的研究成果，指导教师对此进行了审定。本论文由本人独立撰写，文责自负。研究生签名导师签章:年目录中文摘要················································································1英文

3、摘要················································································4英文缩写················································································8研究论文血清CTRP3水平与冠状动脉病变严重程度及侧支循环形成的相关性前言·····························································

4、···················9材料与方法·····································································11结果··············································································17附图··············································································18附表····

5、··········································································19讨论··············································································21结论··············································································23参考文献······················

6、··················································25综述血清CTRP3水平在急性冠脉综合征患者中的研究进展···········26致谢····················································································37个人简历··············································································38中文

7、摘要血清CTRP3水平与冠状动脉病变严重程度及侧支循环形成的相关性摘要目的：冠状动脉粥样硬化性心脏病(cronoaryarteryheartdisease,CHD)，指冠状动脉因狭窄或阻塞导致供血不足从而引起心肌缺血缺氧、机能障碍和（或）器质性疾病，而冠脉严重粥样硬化或者痉挛在狭窄、阻塞病变中最为常见。冠心病是世界范围内致死率最高的疾病之一，美国国家健康统计中心1987年进行的一项全国死因统计，结果表明：心脏病占总死因的35%，位居死因之首，其中冠心病死亡率占据24.1%。急性冠脉综合征(acutecoronarysyndro

8、me,ACS)是以冠状动脉粥样硬化斑块破裂或侵袭，继发完全或不完全的闭塞性血栓形成为病理基础的临床综合征，包括急性心肌梗死(AMI)及不稳定型心绞痛(UA)，其中AMI又分为ST段抬高性心肌梗死(STEMI)及非ST段抬高性心肌梗死(NSTEMI)。众所周知，ACS的发生发展