腰椎终板modic改变与退行性腰椎滑脱的相关性研究

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1、授予单位代码10089学号或申请号13219HebeiMedicalUniversity在职科学学位腰椎终板Modic改变与退行性腰椎滑脱的相关性研究学位申请人：张计成导师：李会杰教授专业：外科学二级学院：第三医院2015年3月河北医科大学学位论文使用授权及知识产权归属承诺本学位论文在导师(或指导小组)的指导下,由本人独立完成。本学位论文研究所获得的研究成果,其知识产权归河北医科大学所有。河北医科大学有权对本学位论文进行交流、公开和使用。凡发表与学位论文主要内容相关的论文,第一署名为单位河北医科大学，试验材料、原始数据、申报的专利等知识产权均归河北医科大学所有。否

2、则,承担相应法律责任。研究生签名:&•导师签驾&级学院领导盖章:(r年r月曰河北医科大学研究生学位论文独创性声明本论文是在导师指导下进行的研究工作及取得的研究成果,除了文中特别加以标注和致谢等内容外，文中不包含其他人已经发表或撰写的研究成果,指导教师对此进行了审定。本论文由本人独立撰写,文责自负。研究生签名导师签軍:…年广月日目录中文摘要·············································································1英文摘要·································

3、············································3研究论文腰椎终板Modic改变与退行性腰椎滑脱的相关性研究前言·············································································6资料与方法····································································6结果·······················································

4、······················9附图·············································································10附表·············································································15讨论·············································································17结论·················

5、····························································22参考文献·······································································23综述腰椎终板Modic改变研究进展··········································27致谢···················································································

6、37个人简历·············································································38中文摘要腰椎终板Modic改变与退行性腰椎滑脱的相关性研究摘要目的：研究腰椎终板Modic改变在退变性腰椎滑脱中的规律，探讨腰椎终板Modic改变、退变性腰椎滑脱、临床症状之间的关联度，为临床治疗退变性腰椎滑脱提供理论支持，提高临床治疗效果。方法：选取2014年1月至2014年12月因下腰痛或坐骨神经痛于我院行手术治疗的退变性腰椎滑脱患者为研究对象，统计并记录患者基本信息，并对所有患者均行腰椎MR

7、I及标准正侧位X线摄像，以滑脱节段椎体为研究对象，在腰椎MRI中线矢状面T2图像上，利用图像分析软件SpineExaminer分别测量终板Modic改变的面积及最大椎体面积，并计算Modic面积改变率（Modic改变面积/最大椎体面积）；拍摄标准站立位腰椎正侧位X线片，借助系统软件测量滑脱椎体后缘与下位椎体后缘之间的距离（AB）及下位椎体矢状径（AC）,并计算椎体滑脱程度（Taillard指数），Taillard指数=AB/AC；测量记录患者入院和复查时的视觉疼痛模拟评分（VAS）及测量并记录Oswestry功能障碍指数（ODI），并计算VAS评分改善率及ODI改

8、善率。比较