天麻素在脊髓背角的镇痛作用及其突触机制研究

《天麻素在脊髓背角的镇痛作用及其突触机制研究》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、分类号R338UDC616-002密级公开天麻素在脊髓背角的镇痛作用及其突触机制研究肖梅梅培养类别全日制学位类型专业学位一级学科(专业类)临床医学二级学科(专业)麻醉学研究方向疼痛机制指导教师董辉副教授（副主任医师）培养单位西京医院麻醉科二O一五年五月第四军医大学硕士学位论文目录缩略语表·······························································································1中文摘要······································

2、·························································3英文摘要·······························································································7前言······························································································13文献回顾······················

3、········································································14正文······························································································24第一部分：验证不同浓度的天麻素对炎性痛小鼠的镇痛作用·························241材料······················································

4、······································241.1实验动物·················································································241.2实验试剂·················································································241.3实验器材·······················································

5、··························242方法····························································································252.1动物模型制备···········································································252.2行为学测试·······························································

6、···············262.3动物分组·················································································272.4统计分析·················································································273结果··················································································

7、··········273.1腹腔注射天麻素对持续性自发痛行为的影响····································273.2腹腔注射天麻素对触诱发痛及痛觉过敏行为的影响···························293.3鞘内注射天麻素对触诱发痛及痛觉过敏行为的影响···························303.4腹腔注射天麻素对正常小鼠基础痛阈和运动协调能力的影响···············314讨论·····················································

8、··························