前列地尔治疗老年高血压所致良性小动脉性肾硬化症临床疗效观察

《前列地尔治疗老年高血压所致良性小动脉性肾硬化症临床疗效观察》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、授予单位代码10089学号或申请号13120令“；儿HebeiMedicalUniversity在职科学学位前列地尔治疗老年高血压所致良性小动脉性肾硬化症临床疗效观察学位申请人：杨阳导师：李星涛教授专业：内科学二级学院：第四医院2015年3月河北医科大学学位论文使用授权及知识产权归属承诺本学位论文在导师(或指导小组)的指导下，由本人独立完成。本学位论文研究所获得的研究成果，其知识产权归河北医科大学所.有。河北医科大学有权对本学位论文进行交流、公开和使用。凡发表与学位论文主要内容相关的论文,第一署名为单位河北医科大学，i试验材料、原始数据、申报的专利等知识产权

2、均归河北医科大学所丨有。否则，承担相应法律责任。7研究生签名导师签章二级学院领导盖章：年月乂日河北医科大学研究生学位论文独创性声明本论文是在导师指导下进行的研究工作及取得的研究成果,除了文中特别加以标注和致谢等内容外,文中不包含其他人已经发表或撰写的研究成果,指导教师对此进行了审定。本论文由本人独立撰写,文责自负。；年广月乂日目录中文摘要·············································································1英文摘要·······························

3、··············································3研究论文前列地尔治疗老年高血压所致良性小动脉性肾硬化症临床疗效观察前言·············································································6材料与方法····································································7结果···············································

4、······························9附表·············································································11讨论·············································································13结论·············································································16参考文献·····

5、··································································16综述前列地尔治疗老年高血压所致良性小动脉性肾硬化症临床疗效观察············································································19致谢···················································································34个人简历···············

6、······························································35中文摘要前列地尔治疗老年高血压所致良性小动脉性肾硬化症临床疗效观察摘要目的：研究前列地尔注射液在治疗老年高血压引起的良性小动脉性肾硬化症的临床疗效；观察前列地尔注射液对肾脏的保护作用；观察前列地尔注射液治疗良性小动脉性肾硬化症的安全性。方法：选择2013年11月到2014年11月在承德市中心医院老年病科住院的老年原发性高血压所致良性小动脉性肾硬化症患者，入选病例共100例，随机分为试验组与对照组。入选患者均符合以下三项诊断标准：一、良

7、性小动脉性肾硬化症的诊断标准，即：①符合原发性高血压诊断标准。②高血压病程一般大于10年。③尿常规提示有轻至中度蛋白尿，尿镜检有形成份少。④常伴随视网膜动脉硬化改变。⑤排除原发、继发性肾脏疾病。二、入选患者均符合2010年由中国高血压联盟和国家心血管病中心颁布的《中国高血压防治指南2010》为依据的高血压诊断标准。三、入选患者均符合我国老年人的诊断标准，即大于60岁。入选前需排除继发性高血压患者；原发、继发肾脏疾病患者；严重心功能不全患者；青光眼及高眼压患者；既往有胃溃疡及消化道出血患者；间质性肺炎患者；糖尿病肾病患者；对前列地尔制剂有过敏史患者；有其他危及生

8、命的严重疾病（如恶性肿瘤等）患者。剔除