促肾上腺皮质激素释放因子1型受体经camppka信号通路对u87mg细胞凋亡机制的研究

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1、授予单位代码10089学号或申请号20122145H妗(E科大5HebeiMedicalUniversity硕士学位论文科学学位促肾上腺皮质激素释放因子1型受体经cAMP/PKA信号通路对U87MG细胞凋亡机制的研究研究生：杨明导师：王立群教授专业：外科学2015年3月河北医科大学学位论文使用授权及知识产权归属承诺本学位论文在导师（或指导小组）的指导下，由本人独立完成。本学位论文研究所获得的研究成果，其知识产权归河北医科大学所有。河北医科大学有权对本学位论文进行交流、公幵和使用。凡发表与学位论文主要内容相关的论文，第一署名为单位河北

2、医科大学，试验材料、原始数据、申报的专利等知识产权均归河北医科大学所有。否则，承担相应法律责任。研究生签名4]导师签章：J4二级学院领导盖章•.乂.•••lo)5年，月乃日河北医科大学研究生学位论文独创性声明本论文是在导师指导下进行的研究工作及取得的研究成果，除了文中特别加以标注和致谢等内容外，文中不包含其他人已经发表或撰写的研究成果，指导教师对此进行了审定。本论文由本人独立撰写，文责自负。研究生签名:导师签章:t年3月工3日目录中文摘要················································

3、····························································1英文摘要············································································································3英文缩写···························································································

4、·················6研究论文促肾上腺皮质激素释放因子1型受体经cAMP/PKA信号通路对U87MG细胞凋亡机制的研究前言············································································································7材料与方法·······················································································

5、·········8结果··········································································································19附图··········································································································21附表·····································

6、·····································································24讨论··········································································································26结论······················································································

7、····················29参考文献··································································································29综述促肾上腺皮质激素释放因子(CRF)、相关肽其受体（CRFR1,CRFR2,CRFR3）信号转导通路的研究进展····················································33致谢·······························

8、···················································································41个人简历····························