硫化氢对脂多糖致大鼠急性肺损伤肺细胞凋亡的影响及其机制

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1、授予单位代码10089学号或申请号20121092奸妗(E科大坌HebeiMedicalUniversity博士学位论文科学学位硫化氢对脂多糖致大鼠急性肺损伤肺细胞凋亡的影响及其机制研究生：杜全胜导师：张建新教授专业：药理学二级学院：河北省疾病预防控制中心2015年4月；可北I医^禾斗.大，学位论文使用授权及知识产权归属承诺本学位论文是在导师（或指导小组）的指导下，由本人独立完成。本学位论文研究所获的研究成果，其知识产权归河北医科大学所有。河北医科大学有权对本学位论文进行交流、公幵和使用。凡发表与学位论文主要内容相关的论文，第一署名单位为河北医科大学，试验材料、原始数据、申报的专利等知识产权

2、均归河北医科大学所有。否则，承担相应的法律责任。河北医科大学研究生学位论文独创性声明本论文是在导师指导下进行的研究工作及取得的研究成果，除了文中特别加以标注等内容外，文中不包含其他人己发表或撰写的研究成果，指导教师对此进行了审定。本论文由本人独立撰写，文责自负。研究生签名:导师签章：2015年5月,欠日目录中文摘要·······································································1英文摘要·································································

3、······9英文缩写······································································19研究论文硫化氢对脂多糖致大鼠急性肺损伤肺细胞凋亡的影响及其机制引言······································································20第一部分脂多糖致大鼠急性肺损伤内源性硫化氢/胱硫醚-γ-裂解酶系统的改变前言······································································21材

4、料与方法······························································22结果······································································24附图······································································27附表······································································33讨论·······

5、·······························································34小结······································································35参考文献································································35第二部分硫化氢对脂多糖致大鼠急性肺损伤肺组织细胞凋亡的影响前言···························································

6、···········37材料与方法······························································37结果······································································39附图······································································40附表···································································

7、···42讨论······································································43小结······································································44参考文献·················································