SSBP1基因遗传变异与胃癌预后的关联分析及分子机制研究.pdf

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1、`分类号：密级：学号：2015211031单位代码：10759石河子大学硕士学位论文SSBP1基因遗传变异与胃癌预后的关联分析及分子机制研究学位申请人李秋晨指导教师郑勇申请学位类别临床医学硕士专业名称临床医学研究领域肿瘤学所在学院医学院中国·新疆·石河子2018年05月AssociationandfunctionalstudybetweengeneticvariationofSSBP1geneandgastriccancerprognosisADissertationSubmittedtoShihe

2、ziUniversityInPartialFulfillmentoftheRequirementsfortheDegreeofMasterofMedicineByLiQiu-chen(Oncology)DissertationSupervisor:Prof.ZhengYongMay,2018目录中文摘要....................................................................................................

3、...........................IAbstract...........................................................................................................................III英文缩略词表....................................................................................

4、...................................V前言.................................................................................................................................1第一章SSBP1基因遗传变异与胃癌预后的相关性研究..................................................31材料.....

5、..............................................................................................................................32方法..........................................................................................................................

6、.........43结果...................................................................................................................................63.1患者基线数据特征及其与胃癌预后的相关性分析...............................................63.2SSBP1基因SNP位点不同基因型与胃癌患者的生存分析.....

7、.............................113.3SNP位点rs6976500基因型对不同分层胃癌患者预后的影响..........................143.4SNP位点rs6976500基因型对TNM分期预测胃癌预后效能的影响..................173.5SNP位点rs6976500基因型对胃癌患者术后化疗敏感应答的影响..................204讨论...........................................

8、......................................................................................23第二章SNPrs6976500基因型影响SSBP1表达的机制研究........................................261材料.......................................................................