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ID:34487235
大小:1.28 MB
页数:36页
时间:2019-03-06
《crrt治疗后sirs患者相关指标的变化及意义》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、CRRT治疗后SIRS患者相关指标的变化及意义摘要目的应用连续性肾脏替代治疗(CRRT)技术治疗全身炎症反应综合征(SIRS),探讨治疗期间病人相关的免疫和炎性指标的变化及意义:同时判断其对预后的影响。方法选取2011年12月至2013年3月入住青岛市立医院ICU的SIRS病人52例,其中常规内科治疗的同时行CRRT治疗的病人26例(CRRT组),仅进行常规内科治疗的病人26例(对照组)。分别于治疗前和治疗结束后采取静脉血检测C一反应蛋白(CRP)、血常规、T细胞亚群,采取动脉血做血气分析。此外,进行急性生理学和慢性健康评估II(APACHEII)评分,并对其进行比较分析。结果1、CRRT
2、组存活19例,死亡7例,存活率73.0896。对照组存活10例,死亡16例,存活率38.46%。2、CRRT组治疗后与治疗前比,CRP、白细胞计数、中性粒细胞计数、单核细胞计数、APACHEII评分、PCO:和血乳酸值下降(P<0.05),CD3+、CD4+和NK细胞增多,有统计学意义(P0.05)。4、CRRT组与对照组治疗前,各指标均无差异(P>O.05)。治疗后比较,CRP、白细胞计数、中性粒细胞计数、单核细胞计数、PH值、PCO:、APACHEII评分
3、、血乳酸、CD3+和CD4+变化有意义(P4、彦教授胡丹副教授关键词:持续肾脏替代治疗:SIRS;T细胞亚群;CRPTHEEFFECTANDSIGNIFICANCEoFRELATEDINDICAToRSWITHSII峪I'ATIENTSTIⅡ己oUGHCIUUlTREATⅣmNTobjectAbstractToevaluatethetheeffectandsignificanceofimmuneandinflammatoryindexonSIRSandtojudgetheprognosisafterthetreatmentofCRRT.MethodsFromDecember201ltoMarch2013,weindentifiedth5、e52casesofpatientswhowereadmittedtoICUofQingdaoMunicipalHospital,includingtheCRRYgroupN=26)whichwereperformedwithroutinetreatmentandcontinuousrenalreplacementtherapy(CRRT)andcontolgroup(N=26)whichonlyacceptedroutinetreatment.Inthetwogroups,theC—reactiveprotein(CRP)concentrations,routinebloodtestan6、dTcellsubsetsfromvenoussamplewererecordedbeforeandaltertreatment,andmeanwhile,bloodgaswererecordedfromarterialsamples.Additionally,therewasacutephysiologyandchronichealthevaluation(APACHEII)SCOre.Results1.Afterthetreatment,therewere19casestosurvive,7deaths,andthesurvivalrateis73.08%intheCRRTgroup.7、Inthecontrolgroup,therewerel0casestosurvive,16deaths,andthesurvivalrateis38.46%.2.IntheCRRTgroup,theCRP,theleukocytecount,theneutrophilcount,monocytecounts,APACHEII’score.PC02andlactateweredecreasedafterCRRT(P<0.
4、彦教授胡丹副教授关键词:持续肾脏替代治疗:SIRS;T细胞亚群;CRPTHEEFFECTANDSIGNIFICANCEoFRELATEDINDICAToRSWITHSII峪I'ATIENTSTIⅡ己oUGHCIUUlTREATⅣmNTobjectAbstractToevaluatethetheeffectandsignificanceofimmuneandinflammatoryindexonSIRSandtojudgetheprognosisafterthetreatmentofCRRT.MethodsFromDecember201ltoMarch2013,weindentifiedth
5、e52casesofpatientswhowereadmittedtoICUofQingdaoMunicipalHospital,includingtheCRRYgroupN=26)whichwereperformedwithroutinetreatmentandcontinuousrenalreplacementtherapy(CRRT)andcontolgroup(N=26)whichonlyacceptedroutinetreatment.Inthetwogroups,theC—reactiveprotein(CRP)concentrations,routinebloodtestan
6、dTcellsubsetsfromvenoussamplewererecordedbeforeandaltertreatment,andmeanwhile,bloodgaswererecordedfromarterialsamples.Additionally,therewasacutephysiologyandchronichealthevaluation(APACHEII)SCOre.Results1.Afterthetreatment,therewere19casestosurvive,7deaths,andthesurvivalrateis73.08%intheCRRTgroup.
7、Inthecontrolgroup,therewerel0casestosurvive,16deaths,andthesurvivalrateis38.46%.2.IntheCRRTgroup,theCRP,theleukocytecount,theneutrophilcount,monocytecounts,APACHEII’score.PC02andlactateweredecreasedafterCRRT(P<0.
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