快速注射结合缓慢融入对比剂在冠状动脉mr血管成像中的应用

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1、484·2010年5月第44卷第5期ChinJRadiol。May2010．Vo1．44．No．5．胸部放射学陕速注射结合缓慢融人对比剂在冠状动脉MR血管成像中的应用李涛赵绍宏蔡祖龙高建华杨立程流泉高元桂【摘要】目的评价快速注射结合缓慢融人对比剂Gd—DTPA对血池T弛豫效果的影响。方法对15例冠心病患者行冠状动脉MRA检查。先以1．50ml／s流率注射对比剂Gd—DTPA10ml，再以0．05ml／s流率注射2Oml，然后对冠状动脉同1支血管行2次扫描，获得注射对比剂后5和15min的图像。计

2、算增强前后图像的信噪比(SNR)和对比噪声比(CNR)，并以t检验进行比较。结果注射对比剂后5min图像的SNR和CNR(35．37±6．84和21．57±6．08)明显高于增强前图像的SNR和CNR(27．38±6．24和13．19±6．50)。注射对比剂15min后图像的SNR(33．81-4-9．43)高于增强前，但没有统计学意义(t=1．885，P=0．074)，图像的CNR(21．204-7．65)明显高于增强前。注射对比剂后5和15min图像的SNR和CNR没有明显的区别。结论快速注

3、射结合缓慢融入Gd—DTPA，可以获得延长短T效应的采样时间，以适应冠状动脉MRA多期扫描的需求。【关键词】磁共振血管成像；冠状血管；造影剂QuickinjectioncombiningwithslowinfusionofcontrastmediaoncoronaryMRangiographyLITao，zHAoShao—hong，CAlzu—long，GAOJian—hua。YANGLi．CHENGLiu—quan，GAOYuan—gui．DepartmentofRadiology，PGene

4、ralHospital，e100853，China(Presentaddress：DepartmentofCT，theGeneralHospitalofChinesePeoplesArmedPoZiceForces，Be100039，Cina)Co~espondingauthor：z爿H0Shao—hong，Email：zhaoshaohong@yahoo．corll,cn【Abstract】0bjectiveToevaluatetheeffectofquickinjectioncombinin

5、gwithslowinfusionofGd—DTPAonT．relaxationoftheblood．MethodsFifteenvolunteerswererecruitedforcoronaryMRAstudyusinganavigator-gated3D-FIESTAsequence．CoronaryMRAwereacquiredonthesamesegmentstwotimesat5minutesand15minutesafterGd—DTPAadministration．Contras

6、tagentwasinjectedbiphasicallywith10mlataflowrateof1．5ml／sand20mlatO．05m1／stoprolongtheT，relaxationeffect．Signa1．to．noiseratio(SNR)andcontrast．to．noiseratio(CNR)werecalculatedpre—andpost—contrastMRA．Imagequalitywascomparedusingt-test．ResultsTheSNRandC

7、NRat5minutesaftercontrastinjectionf35．374-6．84and21．574-6．O8)weresignificantlyhigherthanthatofpre—contrastMRA(27．38±6．24and13．19±6．50)．rheSNRat15minutesaftercontrastiniection(33．81±9．43)washigherthanthatofpre一．contrastMRA．buttherewasnostatisticallydi

8、fference(t=1．885，P=0．074)．TheCNRat15minutesaftercontrastiniection(21．204-7．65)wassignificantlyhigherthanthatofpre—contrastMRA．TheSNRandCNRat15minutesaftercontrastinjectionwerenosignificantdifferentcomparedwiththoseat5minutesaftercontrastiniection．Con