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时间:2019-03-06
《快速注射结合缓慢融入对比剂在冠状动脉mr血管成像中的应用》由会员上传分享,免费在线阅读,更多相关内容在教育资源-天天文库。
1、484·2010年5月第44卷第5期ChinJRadiol。May2010.Vo1.44.No.5.胸部放射学陕速注射结合缓慢融人对比剂在冠状动脉MR血管成像中的应用李涛赵绍宏蔡祖龙高建华杨立程流泉高元桂【摘要】目的评价快速注射结合缓慢融人对比剂Gd—DTPA对血池T弛豫效果的影响。方法对15例冠心病患者行冠状动脉MRA检查。先以1.50ml/s流率注射对比剂Gd—DTPA10ml,再以0.05ml/s流率注射2Oml,然后对冠状动脉同1支血管行2次扫描,获得注射对比剂后5和15min的图像。计
2、算增强前后图像的信噪比(SNR)和对比噪声比(CNR),并以t检验进行比较。结果注射对比剂后5min图像的SNR和CNR(35.37±6.84和21.57±6.08)明显高于增强前图像的SNR和CNR(27.38±6.24和13.19±6.50)。注射对比剂15min后图像的SNR(33.81-4-9.43)高于增强前,但没有统计学意义(t=1.885,P=0.074),图像的CNR(21.204-7.65)明显高于增强前。注射对比剂后5和15min图像的SNR和CNR没有明显的区别。结论快速注
3、射结合缓慢融入Gd—DTPA,可以获得延长短T效应的采样时间,以适应冠状动脉MRA多期扫描的需求。【关键词】磁共振血管成像;冠状血管;造影剂QuickinjectioncombiningwithslowinfusionofcontrastmediaoncoronaryMRangiographyLITao,zHAoShao—hong,CAlzu—long,GAOJian—hua。YANGLi.CHENGLiu—quan,GAOYuan—gui.DepartmentofRadiology,PGene
4、ralHospital,e100853,China(Presentaddress:DepartmentofCT,theGeneralHospitalofChinesePeoplesArmedPoZiceForces,Be100039,Cina)Co~espondingauthor:z爿H0Shao—hong,Email:zhaoshaohong@yahoo.corll,cn【Abstract】0bjectiveToevaluatetheeffectofquickinjectioncombinin
5、gwithslowinfusionofGd—DTPAonT.relaxationoftheblood.MethodsFifteenvolunteerswererecruitedforcoronaryMRAstudyusinganavigator-gated3D-FIESTAsequence.CoronaryMRAwereacquiredonthesamesegmentstwotimesat5minutesand15minutesafterGd—DTPAadministration.Contras
6、tagentwasinjectedbiphasicallywith10mlataflowrateof1.5ml/sand20mlatO.05m1/stoprolongtheT,relaxationeffect.Signa1.to.noiseratio(SNR)andcontrast.to.noiseratio(CNR)werecalculatedpre—andpost—contrastMRA.Imagequalitywascomparedusingt-test.ResultsTheSNRandC
7、NRat5minutesaftercontrastinjectionf35.374-6.84and21.574-6.O8)weresignificantlyhigherthanthatofpre—contrastMRA(27.38±6.24and13.19±6.50).rheSNRat15minutesaftercontrastiniection(33.81±9.43)washigherthanthatofpre一.contrastMRA.buttherewasnostatisticallydi
8、fference(t=1.885,P=0.074).TheCNRat15minutesaftercontrastiniection(21.204-7.65)wassignificantlyhigherthanthatofpre—contrastMRA.TheSNRandCNRat15minutesaftercontrastinjectionwerenosignificantdifferentcomparedwiththoseat5minutesaftercontrastiniection.Con
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