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ID:34164935
大小:5.83 MB
页数:42页
时间:2019-03-03
《结直肠浸润性微乳头状癌的临床病理学特征及其与淋巴结转移的关系》由会员上传分享,免费在线阅读,更多相关内容在教育资源-天天文库。
1、万方数据天津医科人学硕士学位论文Abstractobjective1.Toinvestigatetheclinicopathologicalfeaturesandimmunohistochemicalphenotypesofcolorectaladenocarcinomawithinvasivemicropapillarycarcinoma(IMPC)component.2.Toinvestigatetherelationshipbetweencolorectaladenocarcinomawithinvasivemieropapillarycarcinoma(IMPC)compon
2、ent,lymphovascularinvasion,andlymphnodemetastasis.Methods1.HEstainingandimmunohistochemistrystainingwereusedtoobservetheclinicopathologicalfeaturesandimmunohistochemicalphenotypesin1casesofcolorectaladenocarcinomawithinvasivemicropapillarycarcinoma(IMPC)component.2.131casesofcolorectaladenocarc
3、inomawithinvasivemicropapillarycarcinomacomponentwereevaluatedbyHEstainingandimmunohistochemicalstaining.Themainpathologicalfeatures,percentageofIMPCcomponent,lymphovascularinvasion,andlymphnodemetastasiswereassessed,andcomparedto296casesofconventionalcolorectaladenocarcinoma.Results1.Inthe1cas
4、esofIMPC,6weremalesand5werefemales.Theagerangedfrom26to83years(median61,average59-3).9tumourslocatedinrectumand2locatedinthejunctionofdescendingandsigmoidcolon.Themaximumdiameterofthetumoursrangedfrom1.5cmto6.5cm.6tu_rnoul'Sshowedulceratingshapeand5tumoursshowedulceratedfungatingshape.Microscop
5、ically,allthecarcinomasweremainlycomposedofatypicalcellsarrangedinmicropapillarystructures.5ofthemarepurelyinvasivemicropapillarycarcinoma.Therewerelymphaticinvasionandvenousinvasioninallcases.Regionallymphnodesrevealedmetastasesinallcases.Duringtheoperation,metastasestotheliverin3cases,periton
6、ealdisseminationin1case,andmetastasestotheleftinguinallymphnodesin1caseweredetected.6monthsafteroperation2patientsdied.8monthsafteroperationIMPCmetastasedtotheuterusinIcaseand4monthslaterthepatientdied.36monthsafteroperationIMPCmetastasedtotheliverin1case.6-38monthsafteroperation4patientssurviv
7、alwithfreetumours.4patientswerelostinfollow·upafteroperation.1lI万方数据天津医科大学硕士学位论文2.ThemaximumdiameterofthetumorsoftheIMPCgroupwassignificantlylowerthantheconventionalgroup.Thedegreeofdifferentiation,thelymphnodemetastaticrate,theav
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