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1、分类号学号D201178104学校代码10487密级博士学位论文心肌细胞钠通道分子生物学和药理学及刺槐素对SK通道的抑制作用研究学位申请人:陈魁豪指导教师:李贵荣教授学科专业:药理学答辩日期:2014年5月万方数据ADissertationSubmittedtoHuazhongUniversityofScienceandTechnologyfortheDoctoralDegreeofPharmacologyStudiesonMolecularbiologyandPharmacologyPropertiesofINainCard
2、iomyocytesAndtheEffectofAcacetinonSKCaCurrentCandidate:ChenKui-HaoMajor:PharmacologySupervisor:LiGui-RongDepartmentofPharmacology,TongjiMedicalCollegeofHuazhongUniversityofScience&TechnologyWuhan430030,P.R.ChinaMay,2014万方数据独创性声明本人声明所呈交的学位论文是我个人在导师指导下进行的研究工作及取得的研究成果。
3、尽我所知,除文中已经标明引用的内容外,本论文不包含任何其他个人或集体已经发表或撰写过的研究成果。对本文的研究做出贡献的个人和集体,均已在文中以明确方式标明。本人完全意识到,本声明的法律结果由本人承担。学位论文作者签名:日期:年月日学位论文版权使用授权书本学位论文作者完全了解学校有关保留、使用学位论文的规定,即:学校有权保留并向国家有关部门或机构送交论文的复印件和电子版,允许论文被查阅和借阅。本人授权华中科技大学可以将本学位论文的全部或部分内容编入有关数据库进行检索,可以采用影印、缩印或扫描等复制手段保存和汇编本学位论文。本论文
4、属于保密□,在_____年解密后适用本授权书。不保密□。(请在以上方框内打“√”)学位论文作者签名:指导教师签名:日期:年月日日期:年月万方数据目录缩略语··························································································1中文摘要·······················································································2Abstra
5、ct·······················································································4综述(LiteratureReviewandIntroduction)········································61.心脏离子通道···········································································61.1钠通道··········
6、·······································································61.1.1心脏钠通道的分布、结构和功能············································71.1.2心脏钠通道的调节······························································81.1.3心脏钠通道与疾病·········································
7、·····················91.1.4针对钠通道疾病的治疗······················································131.2钾通道···············································································141.2.1电压门控钾通道(Kv)······················································141.2.2内向整流钾通道(K
8、ir)·····················································151.2.3钙离子激活钾通道(KCa)·················································151.3钙通道·····
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