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1、安徽医科大学硕士学位论文分,责任椎体前缘高度、责任椎体中间高度和局部Cobb'S角进行组内比较,单侧组和双侧组上述指标均明显改善,差异具有统计学意义(p<0.05);对两组间术后腰背部疼痛VAS评分,责任椎体前缘高度、中间高度和局部Cobb'S角进行比较无统计学意义(p>0.05)。而对单侧PKP和双侧PKP的手术时间,透视次数,骨水泥注入量,组间比较有显著性差异,具有统计学意义(p<0.05)。单侧组骨水泥渗透5例,双侧组骨水泥渗透7例;单侧组临近椎体再骨折3例,双侧组临近椎体再骨折5例。75例患者PKP术后骨水泥渗透(8例)合并临近椎体再骨折6例。结论:对于老年人新鲜骨质疏松性
2、胸腰椎椎体压缩性骨折(OVCFs)的治疗,采用单侧和双侧经皮穿刺球囊扩张椎体后凸成形术(PKP)均可取的满意的治疗效果;单侧PKP术与双侧PKP术相比具有手术时间短、透视次数少、骨水泥注射量少、骨水泥渗透率低、临近椎体再骨折率低等优点。所有病例中骨水泥渗漏的病例大多数在随访期间出现临近椎体新发骨折骨折,由于此次研究样本量较小,并且缺乏循证医学等权威信息的支持,初步表明骨水泥渗漏与临近椎体再骨折具有相关性。关键词:单侧穿刺双侧穿刺骨质疏松椎体压缩性骨折经皮椎体后凸成形术4安徽医科大学硕士学位论文AnalysisontheClinicalEffectBetweenUnilaterala
3、ndBi-lateralPKPforOsteoporoticCentrumCompressionFracturesMasterdegreecandidate:LiLongSupervisors:ProfessorMaHuasongSpeciality:surgeryAbstractObjective:Tocomparetheclinicaleffectofunipedicularversusbipedicularper-cutaneouskyphoplasty(PKP)inthetreatmentofosteoporoticvertebralcompressionfractures
4、(OVCFs).Methods:wechose75patientsofosteoporosisvertebralcompressionfreshfraetureswhoacceptedtheoperationofangioplastyconvexvertebralfromPLA306hospitalfromNovember2009toJuly2011.Accordingtothehistory,symptoms,signs,preoperativeX-ray,bonedensity,MRI,diagnosedwithpurefreshosteoporosisverte-bralco
5、mpressionfractures,werenoplaceholderintra-spinalcanal,noneurologicaldamage.Allthosepatientsweregottenfollow-upatleast2years.75patientswithOVCFsweretreatedwithPKP,andtheclinicaldatawereanalysedviarandomisedcon-troltrial.Accordingtoadmissiontime,singularnumbersereoperatedviaunipedicularPKP(38cas
6、es),EvennumberswereoperatedviaunipedicularPKP(37cases);Allpatientsweretreatedviaanti-osteoporosisdrugsandfollowedup24months.Werecordedandcomparedthedatasoftwogroupspatientsbeforeandaftersurgeryrelevantinfor-mation.Sincethedateofhospitalrecordlengthofhospitalstay,bonemineraldensityvalues,bonece
7、mentinjectionquantity,numberofperspective,evaluationofpreoper-5安徽医科大学硕士学位论文ativeandpostoperativepainvisualanalogscale(visualanalogscale,VAS)score,meas-uredthepreoperativeandpostoperativefanteriorflangeheight,responsibilityamongvertebral