肝脏局灶性病变的弹性超声诊断与其与造影超声诊断的对比分析

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1、变。肝脏恶性病灶硬度多较周围肝实质硬，弹性图与二维图径线比＞1。恶性病灶内部质地均匀度与病灶大小相关，病灶越大越不均匀。转移癌病灶典型VTI弹性图可出现“牛眼症”改变。3、肝脏局灶性病灶灰阶超声造影诊断率92.5%。肝脏局灶性病变患者的肝动静脉渡越时间测定以HAVTT1≤10.5s作为肝脏恶性病灶的诊断指标，其敏感性82.1%，特异性83.3%，准确率82.5%。肝脏局灶性病灶灰阶超声造影对肝脏局灶性病灶鉴别诊断价值优于HAVTT的测定。结论ARFI超声弹性成像技术可客观反映肝脏局灶性病变的质地硬度改变，有利于肝脏良恶性局

2、灶性病变的鉴别诊断。灰阶超声造影从微循环方面揭示病灶内部血供变化，其对肝脏局灶性病变的定性诊断优于ARFI弹性超声，但ARFI超声弹性成像技术对解决灰阶超声造影诊断难点十分有利。灰阶超声造影技术与ARFI超声弹性成像技术二者作用互补，联合应用超声弹性成像和超声造影有助于提高病灶的诊断准确率。关键词肝脏局灶性病变，声辐射力脉冲，超声检查，弹性成像，超声造影5万方数据UltrasonicElastographyofFocalLiverLesionsandContrastResearchofUltrasonicElastogra

3、phyandContrast-EnhancedUltrasound(CEUS)AbstractObjectiveThevolunteersandpatientswithfocalliverlesionsunderwentultrasonicelastographyandCEUS,tosummarizethecharacteristicsoffocalliverlesionsonthistwoimaging,explorethevalueofUltrasonicElastographyandCEUSindifferentia

4、ldiagnosisoffocalliverlesions,andexpecttoraisetheaccuracyofultrasoundforfocalliverlesions,especiallyforthesmalllesions.Methods1.184patientswith202focalliverlesionsand15healthyvolunteersunderwentvirtualtouchtissueimaging(VTI)andvirtualtouchtissuequantification(VTQ)

5、.Observedparametersontheelastographyimagesarethelesionsboundary,theuniformityofechointhelesions,echointensityandthesizeontheVTIelastographicimageandcorrespondingB-modeimage.Theshearwavevelocity(SWV)oflesionsandliverparenchymawereobtainedbyconductedVTQ.Werecordthel

6、esionsmaximal,minimum,meanvalue,thediferenceandrelativevalueofthemaximalandminimumvalue,theSWVofliverparenchymaandthediferencebetweenthelesionsandliverparenchyma.2.71patientswith80focalliverlesionsamongthesubjectswereexaminedwithgrayscaleCEUSand40patientshadhepati

7、carterytoveintransittime(HAVTT)measuremented.ThediagnosticcriteriaofCEUSrefertoofeurope.3.TheresultsofultrasonicelastographyandCEUSwerecompared.4.TheresultswerestatisticallyanalyzedwithP＜0.05indic

8、atingsiginificantdiffererces.Result1.Theresultsofultrasonicelastographydisplayedthatthestiffnessofmalignantgroupwashighest,followedbybenigngroupandthenn