上海市女性乳腺癌流行趋势与人群筛查策略分析

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1、万方数据复旦大学硕士学位论文中英文摘要Studyonincidenceandmortalitytrendsandpopulation-basedscreeningstrategiesoffemalebreastcancerinShanghai(Abstract)M．S．Candidate：Ju—zhongKorSuperviser：ProfessorWeiLooobjectives：Inthisresearchweusedage-period·cohortmodel(APCmodel)toanalysisthebreastcancerincidenceandmortality

2、ofShanghaiwomen．BasedonquantitativedescriptionoftheShanghaifemalebreastcancerincidenceandmortalitytrends，welookedforpossiblecausesofbreastcancerthroughexploringfactors，suchasthewayageandcohortimpactsbreastcancerincidenceandmortality．Bymeansofcomprehensivecomparisonofeffectivesandnegativeeff

3、ectofvariouspopulation—basedscreeningstrategies，weputforwardsuitablebreastcancerscreeningprogrammeforChinesepeople．Thisstudyprovidesscientificevidencefortheetiologyofbreastcancerresearchandeffectivepreventionandcontrolmeasures，toreducethediseaseburdenofbreastcancer,futherlyimprovewomen’Shea

4、lthstatus．InthefirstpartAPCmodelwasappliedtotheanalysisofShanghaiwomen’Sbreastcancerincidenceandmortalitydata．Effectofperiodandcohortfactorswereextractedfromshanghaifemalebreastcancerincidenceandmortalitytrends，promptbreastcanceretiologicalclues．InthesecondpartexperienceofShanghaipopulation

5、—basedbreastcancerscreeningwereanalysised．Resultsofdifferentbreastcancerscreeningstrategieswerecomparisedtoputforwardbreastcancerscreeningrecommendations，inordertoofferproposalformakingbreastcancerscreeningguidelinessuitableforChina’Spopulation．Methods：Partone：Wecollectedbreastcancerinciden

6、ceandmortalitydatain1973—2007fromshanghaicancerregistry(SCR)．Datawasstratifiedbyage，periodandcohortfactors．Joinpointmodelwasusedtocalculatetheannualpercentagechange(APC)ofincidenceandmortality．APCmodelwasusedtoestimatemodelparameters，evaluatetheimpactofage，periodandbirthcohortfactorsinincid

7、enceandmortalitytrends．Resultswouldbringupsomecluesabouttheetiologyofbreastcancer．气万方数据墨皇奎堂堡主堂垡堡兰l主茎壅垫至Parttwo：Dataofthreepopulation．basedbreastcancerscreeningprojectinShanghaiwascollected．Breastcancercasesweredetectedthroughfollow—upandreviewofthehistor