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1、提要目的:通过收集慢性肾脏病继发高血压患者的临床资料,探讨肾脏实质性疾病继发高血压病患者的常见临床证候和病理要素分布情况,为临床辨证论治奠定理论基础。方法:根据《中医内科学》中的症状内容,结合《中药新药临床研究指导原则》中的慢性肾脏病和高血压病的证候表现,制定出《慢性肾脏病继发高血压病的临床证候目录池》。首先收集126例慢性肾脏病继发高血压病患者的临床症状、体征及舌象脉象,并进行筛选,保留出现频次在10及以上的症状、体征及舌脉象作为因子分析的基础,然后采用降维因子分析提取公因子,由2名有临床经验的中医主
2、任医师对公因子进行辨证,归纳总结出慢性肾脏病继发高血压病患者的病理要素。结果:经频数、频率描述性分析,得出慢性肾脏病继发高血压病患者的临床证候出现频率较高的依次为:头晕(71.43%)、倦怠乏力(67.46%)、水肿(54.76%)、暗舌(42.86%)、薄苔(47.62%)、白苔(55.56%)、弦脉(53.17%)、滑脉(51.59%);降维因子分析得出15个公因子,可提取出:气虚、阴虚、血虚、水湿、湿浊、湿热、痰、瘀血、肾、脾、肝、心、肺和清窍等病理要素。结论:慢性肾脏病继发高血压患者最常见临床证
3、候为:头晕、倦怠乏力、水肿、舌暗、苔薄白、脉弦滑;慢性肾脏病继发高血压病患者的病理要素涉及:气虚、阴虚、血虚、水湿、湿浊、湿热、痰、瘀;病位在:肾、脾、肝、心、肺和清窍。关键词慢性肾脏病,继发性高血压,病理要素。TheanalysisoftraditionalChinesemedicinesymptomsandtraditionalChinesepathologyelementsinChronickidneydiseasepatientswithhighbloodpressure.Speciality:
4、GynecologyofTCM,theStudyofFemaleSterilityAuthor:LihaifengTutor:Prof.JiaoanqinAbstractPurpose:ThroughcollectingtheCKDinpatientswithhighbloodpressureclinicaldata,discussesthekidneydiseaseofhighbloodpressureinthesecondarysubstantialcommonclinicalandpatholog
5、icalfactorsdistribution.Methods:AccordingtotheinternalmedicineoftraditionalChinesemedicineclinicalresearchguidingprinciple,Combiningwith"theChineseherbalmedicinenewmedicineclinicalresearchguidingprinciple"thechronickidneydiseaseandhypertensionsyndromespe
6、rformance,Develop"thechronickidneydiseasesymptomsofhighbloodpressuredirectorypool".Collecttheclinicalsymptoms,signsoftongueandpulseconditionof126casesofchronickidneydieeaseofhighbloodpressure.,Keeptheclinicalsymptoms,tongueandthepulseconditionappearingin
7、morethan10frequency,asthebasisoffactoranalysis,thenadoptthedimensionreductionfactoranalysisandextractionthemalefactor,thetwodoctorsofhavingclinicalexperiencesaystothefactorsofsyndromedifferentiation,reachtheconclusionofthepathologicalfactorsinthechronick
8、idneydiseasehignbloodpressure.Results:Throughthefrequencydescriptiveanalysis,reachtheCKDofhypertensionclinicalsymptomsofhighfor:dizzy(71.43%),languid(67.46%),edema(54.76%),darktongue(42,86%),thinmoss(47.46%),whitemoss(55.5