加味逍遥散治疗老年卒中后抑郁的临床疗效研究

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1、学校代码：10600学号：092032学位类型：专业学位广西中医药大学硕士学位论文加味逍遥散治疗老年卒中后抑郁的临床疗效研究研究生：张晓璐导师：庞声航教授院系（部所）：第一临床医学院专业：中医内科学研究方向：老年心脑血管疾病完成日期：2012年4月25日目录中文摘要··················································3英文摘要··················································5引言···············································

2、···8正文·················································111资料与方法················································111.1诊断标准················································111.2病例选择标准············································111.2.1纳入病例标准··········································111.2.2排除病

3、例标准·········································121.3研究对象···············································101.3.1病例来源及分组·······································121.3.2一般资料分析·········································131.4治疗及观察方法·········································141.4.1治疗药物·················

4、····························141.4.2治疗方法·············································141.4.3观察指标·············································151.4.3.1疗效性观察指标·····································151.4.3.2安全性观察指标·····································151.5统计学处理································

5、·············152研究结果················································1613讨论················································184结论················································25参考文献··················································26附录··················································30综

6、述··················································39致谢···················································47攻读学位期间发表的学术论文目录··························48广西中医学院研究生学位论文作者声明·····················49个人简历···················································502中文摘要目的：观察加味逍遥散治疗老年脑卒中后抑郁的临床疗效，并与应用百忧解治疗

7、老年脑卒中后抑郁的疗效进行比较，从中探讨中医治疗老年脑卒中后抑郁的优势。方法：本研究选择卒中后抑郁患者进行临床观察，入选的61例患者均符合本文所列诊断标准，利用随机区组设计方法，将61例患者（其中男性29例，女性32例）平均分配到治疗组（加味逍遥散+西药抗抑郁治疗）、对照组（西药抗抑郁治疗）。分别给予相应药物治疗，观测各组治疗前后汉密尔顿抑郁量表(HAMD)评分情况，观测血尿便常规、肝功能、肾功能、心电图变化，作为治疗药物安全性的指标，并对这些观测指标进行比较分析。结果：1、按HAMD减分率评估临床总疗效，治疗组临床显效19例(占61.3