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ID:33102279
大小:1.13 MB
页数:30页
时间:2019-02-20
《无创正压通气辅助治疗重症手足口病临床观察》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、南昌大学硕士学位论文无创正压通气辅助治疗重症手足口病临床观察姓名:黄琰琰申请学位级别:硕士专业:儿科学指导教师:徐南平20120601摘要摘要目的:探讨无创正压通气辅助治疗重症手足口病的疗效。方法:对我院2011年1月至2011年12月就诊的65例重症手足口病患者(2期、3期),观察组30例,对照组35例。对照组按常规方法治疗(米力农、甲泼尼龙、丙种球蛋白等),观察组在常规治疗的基础上加经鼻持续气道正压。观察两组血气、心率、血压、血糖、白细胞、住院时间、病情进展、有创机械通气等情况。结果:观察组和对照组的Pa02分别为(83.6士19.4)mmHg和(71.7
2、+17.5)mmHg两者有显著性差异(P<0.05);观察组和对照组的PaC02分别为(33.4+11.5)mmHg和(36.3+12.8)mmHg两者有显著性差异(P3、);观察组和对照组的白细胞计数分别为(9.3+2.3)x109‘L’1和(9.2+3.6)x10吼L~,两者无显著性差异(P>0.05);观察组和对照组的血糖分别为(5.3+1.7)c/mmpl川L和(5.5-4-1.2)c/mmpl川L两者无显著性差异(P>0.05);观察组和对照组住院时间(9.2士2.1)天和(13.2士4.6)天;两者有显著性差异(P<0.05);观察组和对照组的病情进展:2期观察组有O例进入3期,对照组有7例进入3期,两者有显著性差异(P4、差异(P5、ofseverehand,footandmouthdiseaseMethod:65casesinourhospitalwithseverehand,footandmouthdisease(2,3)wereininvolvedbetweenJanuary201andDecember20l1,whiletheobservationgroupof30patientsandthecontrolgroupof35cases.Theobservationgroupaddnasalcontinuouspositiveairwaypressure(NCPAP)onthebas6、isoftheconventionaltreatment(milrinone,awaveofnylon,gammaglobulinandSOon),observedtwogroupsofbloodgases,heartrate,bloodpressure,bloodglucose,whitebloodcells,durationofhospitalization,diseaseprogression,invasivemechanicalventilationandSOOn.Results:Pa02ofobservationandcontrolgroups,re7、spectively(83.64-19.4)mmHgand(71.74-17.5)mmHg,thetwohavesignificantdifferences(P<0.05);PaC02ofobservationandcontrolgroups,respectively(33.4土11.5)mmHgand(36.3+12.8)mmHg,thetwohavesignificantdifferences(P<0.05);Sa02ofobservationandcontrolgroups,respectively(94.5士15.4)%and(89.34-17.6)%8、,thetwothereisasign
3、);观察组和对照组的白细胞计数分别为(9.3+2.3)x109‘L’1和(9.2+3.6)x10吼L~,两者无显著性差异(P>0.05);观察组和对照组的血糖分别为(5.3+1.7)c/mmpl川L和(5.5-4-1.2)c/mmpl川L两者无显著性差异(P>0.05);观察组和对照组住院时间(9.2士2.1)天和(13.2士4.6)天;两者有显著性差异(P<0.05);观察组和对照组的病情进展:2期观察组有O例进入3期,对照组有7例进入3期,两者有显著性差异(P4、差异(P5、ofseverehand,footandmouthdiseaseMethod:65casesinourhospitalwithseverehand,footandmouthdisease(2,3)wereininvolvedbetweenJanuary201andDecember20l1,whiletheobservationgroupof30patientsandthecontrolgroupof35cases.Theobservationgroupaddnasalcontinuouspositiveairwaypressure(NCPAP)onthebas6、isoftheconventionaltreatment(milrinone,awaveofnylon,gammaglobulinandSOon),observedtwogroupsofbloodgases,heartrate,bloodpressure,bloodglucose,whitebloodcells,durationofhospitalization,diseaseprogression,invasivemechanicalventilationandSOOn.Results:Pa02ofobservationandcontrolgroups,re7、spectively(83.64-19.4)mmHgand(71.74-17.5)mmHg,thetwohavesignificantdifferences(P<0.05);PaC02ofobservationandcontrolgroups,respectively(33.4土11.5)mmHgand(36.3+12.8)mmHg,thetwohavesignificantdifferences(P<0.05);Sa02ofobservationandcontrolgroups,respectively(94.5士15.4)%and(89.34-17.6)%8、,thetwothereisasign
4、差异(P5、ofseverehand,footandmouthdiseaseMethod:65casesinourhospitalwithseverehand,footandmouthdisease(2,3)wereininvolvedbetweenJanuary201andDecember20l1,whiletheobservationgroupof30patientsandthecontrolgroupof35cases.Theobservationgroupaddnasalcontinuouspositiveairwaypressure(NCPAP)onthebas6、isoftheconventionaltreatment(milrinone,awaveofnylon,gammaglobulinandSOon),observedtwogroupsofbloodgases,heartrate,bloodpressure,bloodglucose,whitebloodcells,durationofhospitalization,diseaseprogression,invasivemechanicalventilationandSOOn.Results:Pa02ofobservationandcontrolgroups,re7、spectively(83.64-19.4)mmHgand(71.74-17.5)mmHg,thetwohavesignificantdifferences(P<0.05);PaC02ofobservationandcontrolgroups,respectively(33.4土11.5)mmHgand(36.3+12.8)mmHg,thetwohavesignificantdifferences(P<0.05);Sa02ofobservationandcontrolgroups,respectively(94.5士15.4)%and(89.34-17.6)%8、,thetwothereisasign
5、ofseverehand,footandmouthdiseaseMethod:65casesinourhospitalwithseverehand,footandmouthdisease(2,3)wereininvolvedbetweenJanuary201andDecember20l1,whiletheobservationgroupof30patientsandthecontrolgroupof35cases.Theobservationgroupaddnasalcontinuouspositiveairwaypressure(NCPAP)onthebas
6、isoftheconventionaltreatment(milrinone,awaveofnylon,gammaglobulinandSOon),observedtwogroupsofbloodgases,heartrate,bloodpressure,bloodglucose,whitebloodcells,durationofhospitalization,diseaseprogression,invasivemechanicalventilationandSOOn.Results:Pa02ofobservationandcontrolgroups,re
7、spectively(83.64-19.4)mmHgand(71.74-17.5)mmHg,thetwohavesignificantdifferences(P<0.05);PaC02ofobservationandcontrolgroups,respectively(33.4土11.5)mmHgand(36.3+12.8)mmHg,thetwohavesignificantdifferences(P<0.05);Sa02ofobservationandcontrolgroups,respectively(94.5士15.4)%and(89.34-17.6)%
8、,thetwothereisasign
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