108例颅内动脉瘤血管内介入栓塞临床分析

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1、郑州大学硕士学位论文108例颅内动脉瘤血管内介入栓塞临床分析姓名：裴高油申请学位级别：硕士专业：临床医学硕士指导教师：冯广森201205摘要108例颅内动脉瘤血管内介入栓塞临床分析研究生裴高油导师冯广森郑州大学第二附属医院放射科河南郑州450014目的探讨血管内介入栓塞治疗颅内动脉瘤的疗效，总结临床经验并指导实践。方法采用MDS或GDC对108例颅内动脉瘤患者进行血管内介入栓塞治疗，观察近期、远期疗效，并进行疗效分析。结果完全栓塞98例(90．74％)，不完全栓塞7例(6．48％)，部分栓塞2例(1．

2、85％)，失败l例(O．93％)。发生并发症4例(3．70％)。术后3个月mRS评价，预后良好98例(90．74％)，中度残疾5例(4．63％)，重度残疾1例(0．93％)，死亡4例(3．70％)。随访3"--36个月，部分栓塞1例复发，再行GDC栓塞成功，其余未见复发，动脉瘤不复显影。血管内介入栓塞疗效随介入时机延迟和Hunt．Hess分级升高呈下降趋势，MDS与GDC栓塞无显著性差异。结论血管内介入栓塞是一种安全、可靠、有效的颅内动脉瘤治疗方法。关键词颅内动脉瘤；血管内介入栓塞；临床分析Abstr

3、actClinicalanalysisofInterventionalembolizationon108casesofIntracranialaneurysmspatientsPostgraduate：PeiGao—youSupervisor-Prof．FengGuang—senDepartmentofInterventionalRadiologyTheSecondAffiliatedHospitalofZhengzhouUniversityZhengZhou，Henan，450014，Chinaob

4、jectiveToinvestigatetheefficacyoftheintravascularinterventionalembolizationonintracranialaneurysms，summarizetheclinicalexperienceandguidepractice．MethodsTheMDSorGDCwereusedon108casesofpatientswithintravascularaneurysmstotakeintracranialinterventionalemb

5、olization，therecently,thelong-termefficacywereobserved，andanalyzedtheefficacy．Results98casesofcompleteembolization(90．74％)，7easesofincompleteembolization(6．48％)，2casesofpartialembolization(1．85％)，onecasesWasfailure(O．93％)．Complicationsoccurredon4cases(3

6、．70％)．After3monthstookmRSevaluation，98caseshadgoodprognosis(90．74％)，5casesweremoderatedisability(4．63％)，1caseswasseveredisability(O．93％)，4patientsdied(3．70％)．Thepatientswerefollowedupfor3to38months，1patientswithpartialembolizationwasrecurrent，andwithsuc

7、cessbyre—GDCembolization，theresthadnorecurrence，theaneurysmwasnolongerdeveloping．Theefficacyofendovascularembolizationshowedadownwardtrend、加tllinterventiontimedelayandHunt-Hessgradeincreases．theMDSandGDCembolizationhadnosignificantdifference．IIAbstractC

8、onclusionEndovascularInterventionalembolizationisasafe，reliableandeffectivemethodtotreatintracranialaneurysm，toobtainagoodprognosis，theinterventiontimeshouldbewithin3daysafterhemorrhage．Kevwordsintracranialaneurysms；intravascular