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ID:32422115
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时间:2019-02-04
《高频超声评价系统性红斑狼疮患者肱动脉内皮功能》由会员上传分享,免费在线阅读,更多相关内容在工程资料-天天文库。
1、维普资讯http://www.cqvip.com中国超声医学杂志2005年第21卷第11期Chinese!!!·-——841·-————高频超声评价系统性红斑狼疮患者肱动脉内皮功能王红英邓又斌杨好意毕小军陈斌摘要目的应用高频超声测量系统性红斑狼疮(SLE)患者反应性充血前后肱动脉内径的百分变化率评价肱动脉内皮功能。方法研究对象包括36例系统性红斑狼疮患者(依病程分为sIE1组、sIE2组)和18例健康对照者。应用高频超声测量静息状态下、反应性充血后、舌下含服硝酸甘油后的肱动脉内径,并计算反应性充血和硝酸甘油诱发的内径百分变化率及二者之比。结果sIE1组反应
2、性充血诱发的肱动脉内径百分变化率显著低于对照组(P3、肱动脉内皮功能减低,EIV功能亦会发生改变。EDV与EIV之比(EDV/EIV)比单纯的用反应性充血诱发的肱动脉内径百分变化率更能反映其内皮功能状态。关键词系统性红斑狼疮高频超声内皮功能EvaluationofBrachialArteryEndothelialFunctioninPatientswithSystemicLupusErythematosusbyHighResolutionUltrasOnOgraphyWangHongying,DengYoubin,YangHaoyi,etalDepartmentofMedicalUltrasound,Tong4、jiHospital,TongjiMedicalCollege,HuazhongUniversityofScienceandTechnology,Wuhan430030ChinaAbstract:ObjectiveToevaluatebrachialarteryendothelialfunctioninpatientswithsystemiclupuserythematosuswithpercentchangeinthebrachialarterydiameterinducedbyreactivehyperemiabyhighresolutionu1tra5、sonography.MethodsMeasurementsofbrachialarterydiameterwereperformedbyhighresolutionu1trasonographyduringbaseline,reactivehyperemiaandsublingualnitroglycerinadministrationin36patientswithsystemiclupuserythematosus(SLE1groupandSLE2grouparedifferentiatedbycourseofdiseases)and18health6、ysubjects.Percentchangesinbrachialarterydiameterinducedbyreactivehyperemia(EDV)andinducedbynitroglycerin(EIV)werecalculated.TheratioofEDVandEIVwascalculatedtoo.ResultsThepercentchangeinthebrachialarterydiameterinducedbyreactivehyperemiainpatientswithgroupSLE1wassignificantlylessth7、anthatinhealthysubjects(P8、cantlylessthanthatingroupSLE1(P<0
3、肱动脉内皮功能减低,EIV功能亦会发生改变。EDV与EIV之比(EDV/EIV)比单纯的用反应性充血诱发的肱动脉内径百分变化率更能反映其内皮功能状态。关键词系统性红斑狼疮高频超声内皮功能EvaluationofBrachialArteryEndothelialFunctioninPatientswithSystemicLupusErythematosusbyHighResolutionUltrasOnOgraphyWangHongying,DengYoubin,YangHaoyi,etalDepartmentofMedicalUltrasound,Tong
4、jiHospital,TongjiMedicalCollege,HuazhongUniversityofScienceandTechnology,Wuhan430030ChinaAbstract:ObjectiveToevaluatebrachialarteryendothelialfunctioninpatientswithsystemiclupuserythematosuswithpercentchangeinthebrachialarterydiameterinducedbyreactivehyperemiabyhighresolutionu1tra
5、sonography.MethodsMeasurementsofbrachialarterydiameterwereperformedbyhighresolutionu1trasonographyduringbaseline,reactivehyperemiaandsublingualnitroglycerinadministrationin36patientswithsystemiclupuserythematosus(SLE1groupandSLE2grouparedifferentiatedbycourseofdiseases)and18health
6、ysubjects.Percentchangesinbrachialarterydiameterinducedbyreactivehyperemia(EDV)andinducedbynitroglycerin(EIV)werecalculated.TheratioofEDVandEIVwascalculatedtoo.ResultsThepercentchangeinthebrachialarterydiameterinducedbyreactivehyperemiainpatientswithgroupSLE1wassignificantlylessth
7、anthatinhealthysubjects(P8、cantlylessthanthatingroupSLE1(P<0
8、cantlylessthanthatingroupSLE1(P<0
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