早发2型糖尿病临床特点与相关危险因素分析

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1、HDL．C低于早发女性，P

2、e2diabetesmellitusMasterdegreecandidate：TANGXiulingSupervisor：ProfessorZHANGPingMajor：InternalMedicineAbstractBaekground：Thenumberofpatientswithtype2diabetesisincrea-singandtheageofonsetisdecreasing．Childrenandadolescentswithtype2diabetesarecommonnow．Clinicalcharacteristicsandpathog

3、enesisofearlv．Onsettype2diabetesarenotfullyelucidatedyet．ManyfactorsareinVOlvedinearly．onsettype2diabetes．SomeofpatientshavealreadywithchroniccomplicationsofdiabetesatthebeginningofdiagnosisparticularlyDiabeticmacrovaseulardisease．ThemainreasonofdisabledanddeathwasDiabeticmacrovascu

4、larcomplications．Inthisstudy，wecompareclinicaIdatasofpatientsbetweenearly．onsetandlate—onsettype2diabetes，lookingforindependentriskfactorsofearly．onsettype2diabetes，andfordelayingearly-onsettype2diabetes．Objective：Toinvestigateclinicalcharacteristicsandriskfactorsofpatientswithearly

5、—onsettype2diabetes．Methods：WeselectedhospitalizedpatientsfromJan2009toJan2010，intheDepartmentofEndocrinologyoftheSecondAffiliatedHospitalofDalianMedicalUniversity，withdiagnosisoftype2diabetes，excludingtype1diabetes，gestationaldiabetesandmitochondrialgenemutationdiabetes，538cases(27

6、1menand267women)．And103casesdiagnosisage1essthan40yearsoldand435casesdiagnosisagemorethan40yearsold·Generalinformationsofpatients，familyhistoryofdiabetes，biochemicalandcliniealdataswerecompared．Toanalysisclinicalcharacteristicsandriskfactorsofpatientswithearly-onsettype2diabetes·Res

7、uIts：1．Comparedtolate．onsettype2diabetes，subjectswithearly-onsettype2diabeteshadhigherproportionofmalepatients(72·8％vs45．1％)，higherproportionofsmokingpatients(59．22％v834·48％)，higherproportionofpatientswithpositivefamilyhistory(66·02％vs53．33％)，highernon．alcoholicfattyliverdiseaseprev

8、alencerate(68·9％vs5