颈动脉斑块的性质与其社区高危人群常见危险因素的关系与对颈动脉支架植入术的影响

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1、广州医学院硕士学位论文P=0.000)及心率（F=14.45，P=0.001）明显高于软班组和溃疡斑块组。软斑组深穿支梗死占11.1%（2/18），皮质梗死占89.8%（16/18）,硬斑块出现深穿支梗死占66.7%（6/9），皮质梗死占33.3%（3/9），两组相比具有统计学意义（χ2=6.417，P=0.011）。结论：软斑块组术中球囊扩张时所需压力比硬斑块组小，次数比硬斑块组少；球囊扩张后收缩压及心率有明显下降，但支架植入前后两者无明显改变。硬斑块组术中球囊扩张时需要压力比软斑块组及溃疡斑块组大，次数比软斑块组及溃疡斑块组多；球囊扩张前

2、后血压及心率有明显改变；支架植入前后血压无明显变化，但心率有明显改变。溃疡斑块组术中球囊扩张时需要压力最低，次数比硬斑块组少；球囊扩张前后血压，无明显改变；而心率有明显变化。支架植入前后血压及心率均无明显改变。颈动脉支架植入术后软斑块易导致皮质梗死，而硬斑块易导致深穿支梗死。关键词：颈动脉斑块；球囊扩张；支架植入。4万方数据英文摘要Relationshipbetweenthepropertiesofcarotidplaquesandthecommonriskfactorsofitscommunityhigh-riskpopulationand

3、itsinfluenceoncarotidstentimplantationAbstractPartⅠRelationshipbetweenthepropertiesofcarotidplaquesandthecommonriskfactorsofitscommunityhigh-riskpopulationObjectiveToinvestigatetherelationshipbetweenthepropertiesofcarotidplaquesandthecommonriskfactorsofitscommunityhigh-risk

4、population.MethodsFromJanuary2008toAugust2010,277subjectsfromatherosclerotichigh-riskpopulationinnativecommunitiesunderwentcarotidcolorultrasoundexamination.Univariateandmultivariateanalyseswereusedtoidentifytherelationshipbetweentheproperitiesofcarotidplaques(flat,soft,har

5、dandulcerplaque)andthecommonriskfactors.ResultsUnivariateanalysesshowedthatthedetectionratesofflatandulcerplaqueshadaincreasingtrendwithage.Flatplaquesweredetectedmoreinthesubjectsmorethan80yearsoldthanthoselessthan65yearsold(P<0.01),andulcerplaquesmoreinthesubjectsmorethan

6、80yearsoldthaninthoselessthan80yearsold(P<0.05).5万方数据广州医学院硕士学位论文Furthermore,thedetectionratesofflatplaquesweredecreasedsignificantlyinfemalepopulation(P<0.01)aswellasinhypertensivegroup(P<0.05).Multivariateanalysesdiscoveredthatagewasthekeyriskfactorincreasingnotonlycarotid

7、plaqueformation(OR=1.098,P=0.000)butalsothepropertiesofflatplaques(ORulcer=1.048,P=0.011)(ORflat=1.034,P=0.012)and.ulcerplaquesConclusionsThepropertiesofcarotidplaqueswererelatedtotheage,genderandhypertensionofthehigh-riskpopulation;therearelesssoftplaquesinfemaleandhyperte

8、nsivesubjects,moreflatandulcerplaquesintheelderones.【Keywords】carotidplaque;riskfa