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1、英文摘要不同调脂方案对冠心病经皮冠状动脉介入治疗预后的回顾性研究Aretrospectivestudyoftreatmentoutcomesofdifferentlipid-loweringregimensoncoronaryheartdiseasepatientsundergoingpercutaneouscoronaryinterventionAbstractObjective:Numerousdomesticandlargescale,open,randomized,multicenterintern
2、ationalclinicaltrialsshowthatdyslipidemiaisoneofthemajorriskfactorscausingcoronaryatherosclerosisheartdisease(CHD).Thisstudystudiedthereal-worldsettinginclinicalpracticeusingfivedifferentlipid-loweringregimens,assessingtheadversereactionandthemajoradversec
3、ardiovascularevent,tofindareasonablelipid-loweringregimenforsecondarypreventionofcoronaryheartdisease(CHD)patientsundergoingPCI.Methods:Usingelectronicmedicalrecordsmanagementsystem,patientshospitalizedinthecardiologydepartmentattheSecondAffiliatedHospital
4、ofSoochowUniversityfromJune2009toFebruary2014diagnosedangiographicallyascoronaryheartdisease(CHD)positiveandunderwentsubsequentPCIwasincluded,withanexclusivecriteriaofcardiacinsufficiency,abnormalliverfunction,renalinsufficiency,abnormalthyroidfunction,and
5、malignanttumor.Asaresult,1172patientswereincludedforthisstudy.Accordingtoourreal-worldlipid-loweringregimensofsecondarypreventionforcoronaryheartdisease(CHD)undergoingPCI,patientsweredividedintofivegroups,respectively:lipitor20groups,namelythefirstgroup,pa
6、tientstakingLipitor20mgQN(night)(Pfizer,drugname―atorvastatincalciumtablet‖);Crestor10groups,namelythesecondgroup,patientstakingcrestor10mgQN(AstraZenecaPLC,drugname"rosuvastatincalciumtablet");Lipitor40groups,namelythethirdgroup,patientstakingLipitor40mgQ
7、N;Lipitor+Zetiagroups,namelythefourthgroup,patientstake20mglipitorQN+Zetia10mgQD(onceeveryday)(Merckproduction,drugname"Ezetimibe")andcrestor+Zetiagroups,namelythefifthgroup,patientstakingcrestor10mgQN+Zetia10mgQD.Priortotreatment,sixandtwelvemonthsafterwa
8、rds,extractionofvenousblood,fastinghematicfatquadset(low-densitylipoproteincholesterolLDL-C,high-densitylipoprotein不同调脂方案对冠心病经皮冠状动脉介入治疗预后的回顾性研究英文摘要cholesterolHDL-C,triglyceridesTG,totalcholesterolTC)weredeter