成年猪椎体类骨质疏松性生物力学模型的快速建立

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1、万方数据英文摘要WithTheRapidEstablishmentOfAdultPorcineVertebralSimilarOsteoporosisBiomechanicalModelABSTRACTobjective：ObjectiveWiththerisingproportionoftheworld’Sagingpopulation，duetoosteoporosis-relatedclinicaldiseasecausedbymoreandmore，suchasspondylolisthesis，vertebralfractures，scoliosisandpro

2、ximalfemurfracturesduetoosteoporosiscausedofthesediseases，thecurrentchoiceofsurgicalapproachmostabroadofvertebroplastyballoonvertebroplastyorpediclescrewfixation，intemalfixationthroughscrewplacement，Thesediseaseshavebeenseriousharmtotheelderlyhealthandlivingconditions，increasedtheburdenon

3、societyandfamil．Inthecaseofosteoporosis，duetolossofBMDofthevertebralbody,thecompressionforcegeneratedwhentheexternalforcetothespine，conductedthroughthedisctothevertebmlendplate，tospreadaroundthecenterofthetrabecularbone，thestressisformedinsidethevertebralbody,oncethestressexceedsthestreng

4、thoftrabecularbonecanwithstand，thetrabecularstructurewillbedestroyed，thuslosingthestabilityofthevertebralbody,thevertebralfracturewilloccurwhenthefurtherdevelopmentofthelocalcrack．Asaresultofthevertebralbodyreducedbonemineraldensity,thetrabecularthinning，oftencausedbythefailureoftheoperat

5、ion．Theneedtore-pediclescrewfixationsurgery,thepatientneedstobetakenoutofpediclescrews，themechanicalfixedstrengthofthespinalvertebraemayOCCUrsecondarytoweakenleadingthepediclescrewloose，fractureanddisplacement．Therefore，incaseoftheosteoporosis，howtoimprovethepediclescrewfixationeffectisth

6、econcemtopicofthescholarsinrecentyears．Withthedeepeningstudyoftheosteoporosis，osteoporosismodelappliedmorewidely,especiallythestudyofthebiologicalmechanicsmodelofosteoporosis．Currentlytherepresentativeanimalmodelofosteoporosisspinebiomechanicsstudiesmostarecastratedandfemaleanimalsormedic

7、ationanimals，althoughtheseareconsideredthebestmodel，buttherearestillmanyshortcomings，alongwiththetight3万方数据英文摘要integrationofthemedicine，mechanicsandmaterialsscienceandotherrelateddisciplines，avarietyofnewbonefillingmaterialandnewinternalfixationdevicesareemerging，we