【硕士论文】泄浊化瘀调益脾肾法治疗痛风的临床研究.pdf

《【硕士论文】泄浊化瘀调益脾肾法治疗痛风的临床研究.pdf》由会员上传分享，免费在线阅读，更多相关内容在教育资源-天天文库。

1、泄浊化瘀调益脾肾法治疗痛风性关节炎的临床研究摘要目的：观察泄浊化瘀调益脾肾法治疗痛风性关节炎的lI函床疗效，探讨其作用机理。方法：将56例患者随机分为两组，治疗组32例用泄浊化瘀调益脾肾法基本方(由土茯苓、革薜、何首乌、苍术、泽兰、泽泻、全当归、桃仁、红花、川牛膝等10多味组成)加减治疗，对照组24例用秋水仙碱、别嘌呤醇常规治疗，进行用药前后两组患者血沉、血尿酸、肌苷、尿素氮、主要临床症状、舌苔脉象、综合疗效、不良反应等方面的临床观察。结果：总有效率治疗组87．5％，对照组75％，治疗组优于对照组，两组比较有

2、统计学意义(P

3、itiStreatedwitheliminatingturbid，resolvingbloodstasiS，regulatingandreinforcingspleenandkidneyfollowingtraditionalChinesemedicinewasevaluated，andtheprimarymechanismonhowtheherbaltherapywasexplored．Methods：56caseswithgoutyarthritiSwererandomizedintotwogroups．

4、Thepatientsintreatedgroup(32cases)wasadministeredwiththeherbalmediCjoefollowingeliminatingturbid，resolvingbloodstasis，regulatingandreinforcingspleenandkidneyfollowingtraditionalChinesemedicine，andthebasicprescriptionincludedglabrousgreenbrierrhizome，radixpo

5、lygonimuliflori：eupatorium，waterplantaintuber，angelicaroot，peachseed，floscarthami，cyathulae．Thepatientsincontrolgroup(24cases)weretreatedwithroutinetherapyinWesternmedicine，includingColchicinaandA1lopurin01．Theerythrosedimentation，blooduricacid，carnine，urea

6、nitrogen，majorsymptoms，tongueappearanceandpulsefeelingweretestedbeforeandafterthetreatment．Thecomprehensiveeffectandadverseeffectwereevaluatedinthestudy．Results：The87．5％effectireratewasobtainedinthepatientsoftreatedgroup．and75％effectiverateincontrolgroup．Th

7、edifferencebetweentwogroupswassignificant(P<0．05)．Conclusion：Theherbalmedicinewitheliminatingturbid，resolvingbloodstasis，regulatingandreinforcingspleenandkidneyfollowingtraditionalChinesemedicinecouldbeasafe，effectivewaytotreatgoutyarthritis．KEYWORDS：Herbal

8、medicine；Goutyarthritis，Clinicaltrial4第一章关于痛风研究的文献综述1．1【概述】痛风(Gout)是一组嘌呤代谢紊乱所致的慢性疾病。主要临床特点是体内尿酸产生过多或肾脏排泄尿酸减少，引起血中尿酸升高，形成高尿酸血症(hyperuricemia)以及反复发作的急性痛风性关节炎、尿酸盐结晶沉积(痛风石)、慢性痛风性关节炎和关节畸形等。痛风常累及肾脏而引起慢性间质性肾炎