大鼠撞击伤后血—脊髓屏障的研究

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1、分类号密级国际十进分类号（UDC）第四军医大学学位论文大鼠撞击伤后血-脊髓屏障的研究（题名和副题名）葛冠群（作者姓名）鞠躬教授指导教师姓名第四军医大学基础部神经科学研究所指导教师单位硕士神经生物学申请学位级别专业名称2008.042008.06论文提交日期答辩日期2005年9月至2008年4月论文起止时间第四军医大学学位授予单位独创性声明秉承学校严谨的学风与优良的科学道德，本人声明所呈交的论文是我个人在导师指导下进行的研究工作及取得的研究成果。尽我所知，除了文中特别加以标注和致谢的地方外，论文中不包含其他人已经发表或撰写过的研究成果，不包含本人或他人已申请学位或其他

2、用途使用过的成果。与我一同工作的同志对本研究所做的任何贡献均已在论文中作了明确的说明并表示了致谢。申请学位论文与资料若有不实之处，本人承担一切相关责任。论文作者签名：日期：保护知识产权声明本人完全了解第四军医大学有关保护知识产权的规定，即：研究生在校攻读学位期间论文工作的知识产权单位属第四军医大学。本人保证毕业离校后，发表论文或使用论文工作成果时署名单位仍然为第四军医大学。学校可以公布论文的全部或部分内容（含电子版，保密内容除外），可以采用影印，缩印或其他复制手段保存论文。学校有权允许论文被查阅和借阅，并在校园网上提供论文内容的浏览和下载服务。论文作者签名：导师签名

3、：日期：大鼠撞击伤后血-脊髓屏障的研究研究生：葛冠群学科专业：基础医学（神经生物）所在单位：第四军医大学基础部神经科学研究所导师：鞠躬教授辅导教师：沈学锋博士资助基金项目：国家重点基础研究计划（2003CB515301）陕西省社发攻关项目（2006K15-G1）关键词：脊髓损伤；血-脊髓屏障；免疫球蛋白；大鼠；神经元中国人民解放军第四军医大学2008年05月第四军医大学硕士学位论文目录缩略语表························································································

4、·················································1中文摘要·········································································································································2英文摘要··························································································

5、···············································4前言·········································································································································7文献回顾······························································································

6、···········································8第一部分机械性脊髓损伤型模型··································································81.脊髓撞击伤模型························································································82.脊髓挤压伤模型······················································

7、··································83.脊髓切割伤模型························································································9第二部分脊髓损伤机制··················································································91.原发性损伤···················································