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1、DEPARTMENTONECOMPARISONOFMAMMOGRAPHYANDULTRASONO-GRAPHYINDIAGNOSISOFBREASTCANCERABSTRACTBackgroundBreastcancerisoneofthecommonlymalignantneoplasmsendangeringhealthofwomen.IthasclamberedupthefirstmostcommoncancerinChinesewomeninrecentyears.Arealisticstr
2、ategyforthereductionofbreastcancermortalityratesistodiagnosethediseasewhileitisstillinanearlystage.Mammographyisthemostfrequentlyusedmodalityinscreeningbreastcancerinwesterncountries,nevertheless,itssensitivityofdetectionisreducedinwomenwithradiographi
3、callydensebreasts.ThisisalsoaproblemforChinesewomenwithsmall,densebreasts.Ultrasonographyisveryusefulindetectionoflesions,evenindensebreastswhilelesssensitivetomicrocalcifications.Themeanproblemforradilogistsistoimprovethedetectionofbreastcancerandredu
4、cethefalse-positivebycombinationtheadvantagesofthetwomodalities.PartⅠComparisonofgray-scaleandDopplersonographyindiagnosisofbreastcancerPurpose:Todeterminethevalueofgray-scaleUSandDopplersonographyindifferentiationbreastcancer.Methods:382consecutivepat
5、ientsunderwentgray-scaleUSandDopplerUS,Vrespectively.EachlesioncharacteristicwasdescribedandclassifiedaccordingtotheBI-RADSsystem.Takingcategory1,2and3asbenign,category4and5asmalignant,thencomparedwithhistopathologicaldiagnosis.Results:1.Sensitivity,sp
6、ecificityandPPVforthedescriptor“irregularshape”and“notcircumscribedmargins”were83.7%,69.9%,72.6%and90.2%,69.5%,74.9%,respectively.Ofthemargins,PPVforangularorspeculatedandmicrolobulatedwere94.3%and80%.Sensitivity,specificityandPPVforthedescriptorposter
7、ioracousticfeature“shadowing”andlesionswithcalcificationswere30.7%,94.2%,83.5%and29.8%,92.4%,83.1%,respectively.Thesignof“nonparallelorientation”had32.1%sensitivity,77.9%specifityand60%PPV.2.Penetratingvesselswerefoundin26.3%malignantlesionsand1.9%beni
8、gnlesions.ThemeanvaluesofRIofthemalignantandbenigngroupswere0.78±0.80and0.66±0.10,respectively.ThedifferenceofpenetratingvesselsandRIwassignificant(P<0.05).3.Thesensitivity,specificity,accuracy,PPVandNPVofgray-scaleUSandgray-scalecombin