bmi1和mina53在胃癌组织及淋巴结转移灶中的表达及意义

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1、优秀毕业论文BMI．1和MINA53在胃癌组织及淋巴结转移灶中的表达及意义为96．3％和100％(P>O．05)，MINA53在伴淋巴结转移的胃癌原发灶及其淋巴结转移灶中阳性表达率分别为92．6％和96．3％(P>O．05)，其差异无统计学意义。4．胃癌组织中BMI．1和MINA53的表达与患者的性别、年龄无关(均P>0．05)，而在肿瘤TNM分期和分化程度存在显著性差异(P

2、53在胃癌组织及淋巴结转移灶中的阳性表达率明显增高，且二者表达呈正相关。2．BMI．1和MINA53与胃癌的TNM分期、分化程度等临床病理特征相关，与患者性别、年龄、肿瘤部位之间无相关。关键词：胃癌；淋巴结转移灶；BMI．1；MINA53精品参考文献资料优秀毕业论文万方数据精品参考文献资料优秀毕业论文内蒙古大学硕士学位论文THEEXPRESSIONANDPROGNOSTICVALUEOFBMI．1ANDMINA53INSAMPLESFRoMGASTRICCARCINoMASANDLYMPH．NO

3、DEMETASTASESABSTRACTObjective：ToinvestigatetheexpressionofBMI一1andMINA53ingastriccancerandlymphnodemetastasis，analyzetherelationshipbetweenBMI．1MINA53andclinicpathologicalparameters，evaluatetheirroleandsignificanceindevelopmentofgastriccancer．Methods

4、：TheexpressionofBMI-1anddMINA53proteininGastriccancertissuesandmetastaticlymphnodesandcorrespondingadjacentnormalgastricmucosafrom61patientswasanalyzedusingimmunohistochemicalmethod．Results：1．RatioofpositiveexpressionofBMI-1andMINA53proteiningastricc

5、arcinomaslymphnodemetastaseswas100％and96．3％，respectively，ratioofpositiveexpressionofBMI一1andMINA53proteiningastriccancerwas86．9％and82．O％，respectively，ratioofpositiveexpressionofBMI．1andMINA53proteininadjacentnormalgastricmucosawas6．7％and6．7％，respecti

6、vely，whichwereallsignificantlyhigherthanthatinnormalgastricmucosatissues，thedifferencesbetweengroupsarestatisticallysignificantf，P

7、及淋巴结转移灶中的表达及意义andlymphnodemetastaseswas79．4％and96．3％，respectively(P

8、ant．RatioofpositiveexpressionofBMI-1proteininprimarygastriccarcinomaandlymphnodemetastaseswas96．3％and100％，respectively(P>0．05)，ratioofpositiveexpressionofMINA53proteininlymphnodemetastasesandprimarygastriccarcinomawas92．6％and96．3％，respectively(P>0．05