鸦胆子油乳注射液联合顺铂胸腔灌注治疗肺癌所致恶性胸腔积液的疗效观察

鸦胆子油乳注射液联合顺铂胸腔灌注治疗肺癌所致恶性胸腔积液的疗效观察

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时间:2018-12-09

鸦胆子油乳注射液联合顺铂胸腔灌注治疗肺癌所致恶性胸腔积液的疗效观察_第1页
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1、-英文摘要drenching1daysagoandafterdrenchingaweek,reviewbloodroutineexaminationandobservethedrainageofpleuraleffusion,effusioncolorvariationandachestpain,fever,cough,nauseaandvomitingandbonemarrowdepressionandotheradversereactions.At4weeksaftertheendoftreatmentwereobserveda

2、ftertreatmentefficacyevaluation,evaluationofthequalityoflifeandtoxicityevaluaoftheclinicalobservationofbruceajavanicaoilinjectionandcisplatininfusedinthoraxintreatmentofmalignantpleuraleffusioncausedbylungcancer.AlldatasuseSPSS19.0softwaretostatisticalanalysis.Results1

3、objectiveresponserate:Completeremissionin15casesintheobservationgroupandpartialremissionin11cases,stabilityin3cases,progress1.controlgroupcompleteremissionin8cases,partialremission10cases,stablein8cases,progressin4cases.Theobjectiveresponserateoftheobservationgroupandt

4、hecontrolgroup,are86.7%and60%respectively,observationgroupwassignificantlyhigherthanthecontrolgroup,thedifferencebetweenthetwogroupsisstatisticallysignificant(P<0.05).2centersfordiseasecontrolrate:Thediseasecontrolratesoftreatmentand controlgroupsare96.6%and86.6%,Andth

5、edifferencebetweenthetwogroupsis statisticallysignificant(P<0.05).3qualityoflife:Theobservationgroupandthecontrolgroupcontinuedto improvethequalityoflifepatients≥21daysare90.0%and66.7%.theobservation groupissignificantlybetterthanthecontrolgroup,thedifferencebetweenthe

6、two groupswasstatisticallysignificant(P<0.05).4toxicity:Theobservationgroupandthecontrolgroupduringthetreatment period,andnoobviousseriouscomplicationssuchashemorrhage,pneumothorax,and nodeaths.Themajortoxicreactionsbetweentheobservationgroupandthecontrol grouparechest

7、painandfever,andrashes,nauseaandvomiting,theyareinⅠ~Ⅱ, noⅢ~Ⅳoftoxicreactionsandresolvedafterbysymptomatictreatment.11cases ofchestpainintheobservationgroupand10casesoffever,nauseaandvomitingin2 cases,2casesofaskinrash,leukopenia,0;controlschestpainin10cases,9casesof5--

8、----鸦胆子油乳注射液联合顺铂胸腔灌注治疗肺癌所致恶性胸腔积液的疗效观察feverandrashin3,2caseofnauseaandvomiting,neutropeniain3case.Andthereisnostatisti

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