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1、奥美拉哇和雷尼替丁治疗反流性食管炎的疗效对比广丙柳州市潭中人民医院内二科广丙柳州545001摘要:目的:对比奥美拉唑和雷尼替丁治疗反流性食管炎的疗效。方法:选取2013年9月——2015年9月木院收治的反流性食管炎患者共100例,作为观察对象,将患者随机分为观察组和对照组(各50例),对照组患者给予雷尼替丁治疗;观察组患者应用奧美拉哇和雷尼替丁治疗,对比采用不同治疗药物,两组患者的疗效。结果:对比两组患者采用不同治疗药物后的疗效,观察组患者的总有效为92.00%,明显高于对照组的74.00%;两组患者的反流性食管炎症状评分(应用GERL评定法评定)对比,观察组患者的反酸、上腹饱胀
2、、胃部灼热、胸骨后疼痛评分(反酸、上腹饱胀、胃部灼热、胸骨后疼痛评分是(3.72&pluSmn;0.46)分,(3.41±0.89)分,(3.89±0.85)分,(3.85±l.ll)分)明显高于对照组患者的评分(反酸、上腹饱胀、胃部灼热、胸骨后疼痛评分分别是(1.45±0.64)分,(1.27±0.42)分,(1.76±0.45)分,(1.58±0.95)分)。组间对比有显著性差异,PC0.05,具有统计学意义。结论:在临床上,在对反流性食管炎患者进行治疗时,应用奥美拉唑和雷尼替丁
3、治疗,可提高患者治疗有效性,改善患者反酸、上腹饱胀、胃部灼热、胸骨后疼痛症状。关键词:奥美拉唑:雷尼替丁:反流性食管炎;疗效【中图分类号】R730.53【文献标识码】A【文章编号】1001-5213(2016)08-0324-01Abstract:Objective:Tocomparetheefficacyofomeprazoleandranitidinetreatmentofrefluxesophagitis.Methods:September2013-September2015patientswithrefluxesophagitishospitaladmittedatota
4、lof100cases,astheobjectofobservation,patientswererandomlydividedintotwogroupsandthecontrolgroup(50patients)andcontrolgrouppatientsgivenranitidinetherapy;observationgroupwereomeprazoleandranitidinetherapy,comparedtotheuseofdifferentdrugs,theefficacyofthetwogroupsofpatients.Results:Thecompariso
5、noftwogroupsofpatientswithdifferenttherapeuticefficacyofthedrugafterthepatient'stotaleffectiveobservationgroupwas92.00%,significantlyhigherthan74.00%;twogroupsofpatientswithrefluxesophagitissymptomscores(applicationGERLevaluationmethodevaluation)incontrast,patientsintheobservationgroup,acidre
6、flux,bloating,stomachburning,chestpainscore(acidreflux,bloating,stomachburning,chestpainscorewas(3.72±0.46)points(3.41±0.89)points,(3.89±0.85)points,(3.85±1.11)points)scorewassignificantlyhigherinpatients(acidreflux,bloating,stomachburning,chestpainscorewere(1.45&p
7、lusmn;0.64)points,(1.27±0.42)points,(1.76±0.45)points,(1.58±0.95)points).Comparisonbetweenthetwogroupswassignificantdifference,P<0.05,statisticallysignificant.Conclusions:Inclinicalpractice,atthetimeofpatientswithreflu