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时间:2018-12-07
《小儿麻醉前清醒、镇静中右美托咪啶经鼻给药的临床效果》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、小儿麻醉前清醒、镇静中右美托咪噪经鼻给药的临床效果(1.庆元县人民医院浙江庆元323800;2.丽水市中心医院浙江丽水323000)【摘要】目的:探讨术前经鼻滴注中右美托咪唳在小儿麻醉前镇静中的应用效果。方法:选择小儿外科行手术的患儿126例,用随机数字表法将患儿分为M组(咪卩坐安定组)与D组(右美托咪噪组)每组63例。M组经鼻滴注咪卩坐安定0.2mg/kg,D组经鼻滴注右美托咪®2.0µg/kgo分别经鼻给药前(门)、给药后5分钟仃2)、给药后15分钟(T3)、入手术室麻醉诱导前(T4),对患儿进行镇静评分、行为评分登记,记录相关生命体征。结果:M组患儿入睡时间短
2、于D组,T3、T4时M组患儿的镇静评分与行为评分均低于D组,M组患儿的氧饱和度变化与D组比较差异有统计学意义P<0.05;T4时D组患儿的HR下降与M组比较差异有统计学意义P<0.05。结论:经鼻给予右美托咪噪2.0µg/kg能有效的改善患儿术前的焦虑状态,麻醉起效后不影响患儿的呼吸,能安静地与父母分离,麻醉诱导时患儿合作,提高了麻醉诱导期患儿的舒适性。【关键词】小儿;右美托咪噪;经鼻给药;清醒;镇静【中图分类号】R739【文献标识码】B【文章编号】1004-6194(2015)02-0175-02Clinicaleffectsofintranasala
3、dministrationofdexmedetomidineonchildrenwithclearconsciousunderpreanesthesiasedationFanXiaominglWangChuanguang2GaoLijuan2ShenShangronglCaiHuanyoulWuWei2ZhangHeng2(1QingyuanPeople’sHospital,ZhejiangQingyuan,323800;2LishuiCenterHospital,ZhejiangLishui,323000)【Abstract]Objective:Toinvesti
4、gatetheeffectsofpreoperativeintranasaladministrationofdexmedetomidineforchildrenunderpreanesthesiasedation.Methods:126casesofchildrenwithpediatricoperationwererandomizedintogroupM(midazolamgroup,n二63)andgroupD(dexmedetomidinegroup,n二63).GroupMwasgivenintranasaladministrationofmidazolam(0.2mg
5、/kg)whilegroupDwasgivenintranasaladministrationofdexmedetomidine(2.0µg/kg).Sedationscoresandbehaviorscoresofthechildrenwererecordedbeforeadministration(Tl),5min(T2)and15min(T3)afteradministrationandbeforeanesthesiainduction(T4),andthecorrespondingvitalsignswererecorded.Results:Children
6、ingroupMhadshortertimetofallasleepthangroupD.TheirsedationscoresandbehaviorscoresatT3andT4werelowerthangroupD.TherewerestatisticallysignificantdifferencesbetweengroupMandgroupDinoxygensaturationchange(P<0.05);andinHRdecreaseatT4(P<0.05).Conclusion:lntranasaladministrationofdexmedetomid
7、ine(2.0µg/kg)caneffectivelyimprovethepreoperativeanxietyofchildren,butdoesnotaffectthechildren’sbreathafteranesthesia.Sothechildrencanbeseparatedfromtheirparentsquietly,andbecooperatedduringinductionofanesthesia,soastoimprovethechildren
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