资源描述：
《鹿哈合剂防治绝经后骨质疏松症临床研究》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。
1、鹿哈合剂防治绝经后骨质疏松症临床研究【摘要】目的：观察鹿哈合剂对绝经后骨质疏松症的临床疗效。方法：将120例绝经后骨质疏松症患者随机分为治疗组和对照组，每组60例。治疗组给予鹿哈合剂治疗,对照组给予仙灵骨葆胶囊治疗。2组疗程均为6个月。观察2组治疗前后临床症状、体征评分及骨密度、骨代谢指标变化情况。结果：治疗后，2组临床症状、体征积分均较治疗前降低（P0.05）；2组血清雌二醇含量较治疗前升高，治疗组优于对照组，差异有统计学意义（P<0.01）；2组血清骨碱性磷酸酶、I型胶原交联竣基末端肽含量较治疗前降低，治疗组优于对照组，差异有统计学意义（P〈0.01）o结论：鹿哈合剂能
2、够改善绝经后骨质疏松症患者的临床症状，提高患者雌激素水平，降低骨碱性磷酸酚、I型胶原交联竣基末端肽水平，对绝经后骨质疏松症冇防治作用。【关键词】绝经后骨质疏松症；鹿哈合剂；骨密度；骨代谢标志物ClinicalStudyonthePreventionandTreatmentofPostmenopausalOsteoporosiswithLuhaHeji（鹿哈合剂）WANGDan-hui,WANGDan-tong,WEIFeng-juan,ZHAOHong-feng,YANGZhen,JINYing,LIUZhen-kun,WANGZhao-hui[ABSTRACT]Objec
3、tive：ToobservetheclinicaleffectofLuhaHeji（鹿哈合剂）onpostmenopausalosteoporosis.Methods：Onehundredandtwentycasesofpostmenopausalosteoporosiswererandomlydividedintoatreatmentgroupandacontrolgroup,60casesineach.ThetreatmentgroupwastreatedwithLuhaHeji,whilethecontrolgroupwithXianlinggubaoJiaonang
4、(仙灵骨葆胶囊).Aftersix-monthtreatment,thetwogroupswereobservedontheaspectsofchangesofclinicalsymptomsandsignscoresandindexesofbonomineraldensityandbonemetabolism.Results：Aftertreatment,thesignscoresofthetwogroupsweresignificantlylowerthanthosebeforetreatment(P0.05).Theserumestradiollevelsinthet
5、wogroupswerehigherthanbeforetreatment,andthetreatmentgroupwasbetterthanthecontrolgroup,thedifferencebeingstatisticallysignificant(P<0.01).ThecontentsofserumbonealkalinephosphataseandtypeIcollagencross-linkedcarboxylterminalpeptideofthetwogroupswerelowerthanbeforetreatment,andthetreatmentgr
6、oupwasbetterthanthecontrolgroup,thediffercnccbeingstatisticallysignificant(P<0.01)•Conclusion：LuhaHejicanimproveclinicalsymptomsofosteoporosispatients,increasetheirestrogenlevelsanddecreasethelevelsofbonealkalinephosphataseandtypeIcollagencross-linkedcarboxyterminalpeptide,availableforthep
7、reventionandtreatmentofpostmenopausalosteoporosis.[Keywords}postmenopausalosteoporosis；LuhaHeji(鹿哈合剂）；bonemineraldensity；bonemetabolismmarker绝经后骨质疏松症(posrmenopausalosteoporosis,PMOP)是妇女绝经后雌激素降低导致低骨量和全身性骨脆性增加性疾病，主要表现为胸背部疼痛，容易畸形并导致骨折，老年妇女骨质疏松症发生率高达50%〜70%,给家庭和社会
