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1、七氟醚全凭吸入麻醉在早产儿光凝术中的应用曹丽君肖艳英陈国莲(中南大学湘雅二医院麻醉科410011)【摘要】目的：观察七氟醚全凭吸入麻醉应用于早产儿视网膜激光光凝术的可行性。方法：限期住院早产儿视网膜病变患儿28例，矫正胎龄34〜40周，患儿入室后，warm-touch加垫毯保温，调节七氟醚挥发罐刻度至6%，空氧混合气流量5L/分，以面罩吸入七氟醚，待患儿下颌松驰、呼吸明显减弱，呼末七氟醚浓度上至5%后行气管扦管，术中吸入3%〜4%七氟醚维持麻醉，机控呼吸，术毕停七氟醚吸入，空氧混合流量增至5L/分。结果：所
2、有患儿均顺利完成手术；6分钟内所有患儿恢复体动及自主呼吸，13分钟内均拔除气管导管，送NICU。结论：七氟醚全凭吸入麻醉成用于早产儿视网膜光凝手术中安全有效，且苏醒平稳迅速。【关键词】七氟醚早产儿视网膜病变视网膜光凝【中图分类号】R614【文献标识码】A【文章编号】2095-1752(2013)22-0376-02SevofluraneinhaledanesthesiainapplicationinlaserphotocoagulationoperationLijunCAO,YanYingXIAO,Guol
3、ianCHENTheSecondXiangyaHospitaloftheCentral-SouthUniversity,Changsha,Hunana410011,P.R.China【Abstract】Objective:toobservethefeasibilityofsevofluraneinhalationanesthesiaforprematureinfantsundergoinglaserphotocoagulationforretinopathyofprematurity(ROP).Method
4、s:28casesofhospitalizedprematureinfant(thecorrectedgestationalagewas34〜40weeks)withROP,aftertheprematureinfantsbringintooperatingroom,awarmtouch-paddedblanketinsulation,subjectsspontaneouslybreathed6%sevofluranebymask(emptyoxygenmixedflowwas5l/min),afterja
5、wrelaxation,breathingdecreasedsignificantly,andEnd-tidalsevofluraneconcentrationupto5%,theprematureinfantweretreatedwithtrachealintubation,mechanicalcontrolbreath,inhalation3%〜4%sevofluranemaintenanceofanesthesia,whentheoperationwasfinished,stoppedsevoflur
6、aneinhalation,emptyoxygenmixedflowincreasedto5l/min.Results:allpatientsweresuccessfullycompletedoperation,within6minutestheprematureinfantsrestoredbodymovementandspontaneousbreathing,within13minutestheendotrachealtubewasbeenpulled,andthentransferredtoNICU.
7、Conclusion:sevofluranebyinhalationanesthesiaappliedinlaserphotocoagulationoperationforROPissafeandeffective,andsmoothwakeupquickly.【Keywords】sevofluranePrematureinfantretinapathologicalchangeslaserphotocoagulation随着早产儿抢救成功率的提高，早产儿视网膜病变（retinopathyofprematu
8、rityROP）的发生率明显提高。早产儿及低体重新生儿发育未成熟的视网膜血管对氧极其敏感，当长吋间高浓度吸氧吋极易导致ROP［1］。ROP常常在新生儿期间侵犯正在发育的视网膜血管，并可留下永久性损害，或最终导致失明，及吋有效的视网膜激光光凝手术是0前治疗ROP的有效方式［2】。1资料与方法1.1资料限期住院的ROP患儿28例，其中男性16例，女12例（其中双胞胎7对），孕期28〜32周，手术吋矫正胎龄33〜40周
