临床医学毕业论文青年人胃癌的临床研究

《临床医学毕业论文青年人胃癌的临床研究》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、青年人胃癌的临床研宄姓名：2014年6月25日青年人胃癌的临床研究【摘要】H的探讨青年人冑癌的发病特点及临床病理特征。方法回顾分析64例青年人爾癌($35岁)和185例老年人胃癌(260岁)的临床资料。比较两组患者的临床症状、幽门螺杆菌(Hp)感染、病变部位、病程、Borrmann分型、病理类型及预后。结果青年组胃癌女性多发，男女之比为1:1.78,临床首发症状以上腹部疼痛、上腹部饱胀等为主，Hp感染率明显高于老年组(P0.05);青年组病程以3个月、老年组以6个月为主(P0.01)。青年组胃癌发病部位以胃

2、窦为主，老年组以胃底贲门多见(P0.01)。青年组病理类型以BorrmannllhIV型和低分化腺癌多见，老年组以高分化腺癌居多(P0.01或P0.05)。5年生存率青年组低于老年组(P0.05)。结论与老年人胃癌相比，青年人胃癌恶性程度高，分化低，进展速度快，预后差。早期发现、尽早实施根治手术切除是提高治愈率和生存率的关键。【关键词】胃肿瘤;青少年;病理学，临床Abstract:ObjectiveToinvestigatetheclinicalsymptomsandtheclinico-pathologi

3、calcharacteristicsinyoungpatientswithgastriccarcinoma.MethodsTheclinicalpathologicalrecordsof64youngpatients(aged35yearsoryounger)and185elderlypatients(aged60yearsorolder)wereretrospectivelyanalyzed.Clinicalmanifestation,Helicobacterpyloriinfection，lesionl

4、ocation,diseasecourse，Borrmanntyping,pathologicaltypeandprognosisbetweenthetwogroupswereanalyticallycompared.ResultsIntheyouthgroup,thereweremorefemalepatients，theratioofmaletofemalewas1:1.78.Thereweremorecaseswithepigastriumpain，epigastriumdistendasthefir

5、stoccurredclinicalmanifestation.Helicobacterpyloriinfectioncasesinyouthgroupweresignificantlymorethanthoseinelderlygroup(P0.05).Durationofdiseaseintheyouthgroupwaslessthan3months，andtheelderlygroupwaslongerthan6months(P0.01).Thetumorsitesoforiginintheyouth

6、groupweremainlylocatedingastricsinus，andtheelderlygroupmainlyingastriccardia(P0.01).Pathologicfeatures，BorrmannIIIorIVandpoorlydifferentiatedadenocarcinomawereprevalentintheyouthgroup，andwelldifferentiatedadenocarcinomawereprevalentintheelderlygroup(P0.01o

7、rP0.05).The5-yearsurvivalratewasobviouslylowerintheyouthgroupthanthatinelderlygroup(P0.05).ConclusionComparedtotheelderly，youngpatientswithgastriccarcinomascarryworsedegree,lowerdifferentiation，fasterprogressandpoorerprognosis.Earlyidentification，radicalre

8、sectiontreatmentarenecessarytoimprovecurativeandsurvivalratesforyoungpatients.Keywords:stomachneoplasms;adolescence;pathology,clinical胃癌是世界范围内最常见的恶性肿瘤之一，位居癌症死因的第二位［1］。其发病高峰为50〜70岁，近年來青年人胃癌有增多趋势［2］。而青年人胃癌又有其特殊